Transcription Factor

Accessions: UP00219A (UniPROBE 20160601)
Names: AA407197, CCAAT displacement protein, CDP, cut-like 1 (Drosophila), Cutl1, Cux, Cux-1, Cux1, Homeobox protein cut-like 1, Homeobox protein Cux, Kiaa4047, MGC102214, mKIAA4047, Phox2, Protein CASP
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P70403
Description: cut-like 1 (Drosophila)
Length: 93
Pfam Domains: 17-73 Homeobox domain
37-70 Homeobox KN domain
Sequence:
(in bold interface residues)
1 GIDYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTV 60
61 INWFHNYRSRIRRELFIEEIQAGSQGQAGASDS
Interface Residues: 17, 18, 19, 20, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 3cmy_A, 1fjl_B, 3d1n_M, 1ig7_A, 5zfz_A, 6a8r_A, 6m3d_C, 2lkx_A, 1nk2_P, 3lnq_A, 6es3_K, 7q3o_C, 2hos_A, 4xrs_G, 2d5v_B, 1au7_A, 5hod_A, 3l1p_A, 2hdd_A, 3a01_E, 1le8_A, 4j19_B, 2xsd_C, 7xrc_C, 1e3o_C, 2h1k_B, 6fqp_B, 4qtr_D, 1o4x_A, 1du0_A, 1jgg_B, 6fqq_E, 4xrm_B, 1puf_B, 8g87_X
Binding Motifs: UP00219A_1 rccgrtTrATyAmswbr
UP00219A_2 tarTgATrATcAmta
Binding Sites: AGTGATCA
ATGATCAA
ATGATCAC
ATGATCAT
ATTGATCA
ATTGATTA
CCTAATCA
CCTGATCA
CTAATCAA
CTGATCAA
CTTAATCA
CTTGATCA
CTTGATTA
GATGATCA
GATTAATC
GTGATCAA
GTTGATCA
TATGATCA
TTAATCAA
TTGATCAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.