Transcription Factor

						

			
Accessions: T049038_1.02 (CISBP 1.02), CTCF_MOUSE (HOCOMOCO 10)

			
Names: Ctcf, T049038_1.02;, 11-zinc finger protein, CCCTC-binding factor, CTCF_MOUSE, CTCFL paralog, Transcriptional repressor CTCF
Organisms: Mus musculus
Libraries: CISBP 1.02 1, HOCOMOCO 10 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]

2 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Notes: experiment type:ChIP-seq, family:C2H2 ZF
Length: 736
Pfam Domains:   266-288 C2H2-type zinc finger
  266-288 Zinc finger, C2H2 type
  280-305 Zinc-finger double domain
  294-316 C2H2-type zinc finger
  294-316 Zinc finger, C2H2 type
  309-333 Zinc-finger double domain
  322-345 C2H2-type zinc finger
  322-345 Zinc finger, C2H2 type
  337-360 Zinc-finger double domain
  366-387 Zinc-finger double domain
  379-401 C2H2-type zinc finger
  379-401 Zinc finger, C2H2 type
  394-417 Zinc-finger double domain
  407-430 C2H2-type zinc finger
  437-460 C2H2-type zinc finger
  437-460 Zinc finger, C2H2 type
  468-489 C2H2-type zinc finger
  482-504 Zinc-finger double domain
  512-533 Zinc-finger double domain
  523-546 C2H2-type zinc finger
  538-566 Zinc-finger double domain
  555-577 C2H2-type zinc finger
  555-576 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MEGEAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQM   60
  61 VMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPV  120
 121 PVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQ  180
 181 GELPPQEDSSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEV  240
 241 NAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCG  300
 301 RAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYAS  360
 361 VEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSG  420
 421 TMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERY  480
 481 ALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDM  540
 541 HFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKR  600
 601 KMRSKKEDSSDSEENAEPDLDDNEEEEEPAVEIEPEPEPQPQPPPPPQPVAPAPPPAKKR  660
 661 RGRPPGRTNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQAATTDA  720
 721 PNGDLTPEMILSMMDR
Interface Residues: 266, 276, 277, 278, 279, 280, 283, 304, 305, 307, 308, 311, 332, 333, 334, 335, 336, 338, 339, 341, 342, 343, 346, 362, 363, 364, 365, 367, 368, 369, 386, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 417, 418, 419, 420, 421, 423, 424, 425, 428, 447, 448, 449, 450, 451, 454, 457, 477, 478, 480, 481, 484, 490, 504, 505, 506, 507, 508, 509, 512, 516, 533, 534, 535, 536, 537, 538, 540, 544, 565, 566, 568, 569, 572
3D-footprint Homologues: 2kmk_A, 7y3l_A, 7w1m_H, 2gli_A, 6jnm_A, 6a57_A, 6e94_A, 1ubd_C, 7n5w_A, 8ssu_A, 5kkq_D, 5yj3_D, 5ei9_F, 8ssq_A, 8h9h_G, 7ysf_A, 2jpa_A, 6blw_A, 6u9q_A, 4x9j_A, 1f2i_J, 1g2f_F, 5kl3_A, 7txc_E, 6ml4_A, 5v3j_F, 4m9v_C, 2lt7_A, 8cuc_F, 3uk3_C, 2wbs_A, 8gn3_A, 5k5i_A, 1llm_D, 7y3m_I, 2drp_D, 5yel_A, 5k5l_F, 1tf3_A, 1tf6_A
Binding Motifs: M6125_1.02 CCAsyAGrkGGCrsy
CTCF_MOUSE.H10MO.A|M01046 yggCCasyAGrGGGCRsyvk
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.