Transcription Factor

Accessions: T015174_1.02 (CISBP 1.02), USF1_MOUSE (HOCOMOCO 10)
Names: T015174_1.02;, Usf1, Major late transcription factor 1, Upstream stimulatory factor 1, USF1_MOUSE
Organisms: Mus musculus
Libraries: CISBP 1.02 1, HOCOMOCO 10 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 310
Pfam Domains: 200-254 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVKYVFRTENGGQVM 60
61 YRVIQVSEGQLDGQTEGSGAISGYPATQSMTQAVIQGAFTSDDAVDTEGAAAETHYTYFP 120
121 STAVGDGSGGTTSGSTTAVVTTQGSEALLGQATPPSTGQFFVMMSPQEVLQGGSQRSIAP 180
181 RTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSK 240
241 GGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHG 300
301 LEVVIKNDSN
Interface Residues: 201, 203, 204, 205, 207, 208, 211, 212, 216, 238, 240
3D-footprint Homologues: 1a0a_B, 1an4_A, 7xi3_A, 5v0l_A, 7rcu_E, 5gnj_I, 6g1l_A, 4h10_A, 7ssa_L, 5i50_B, 1am9_A, 7xq5_A, 7d8t_A, 4zpk_A, 5nj8_D, 7f2f_B, 5eyo_A, 2ypa_B, 8osl_P, 7xhv_B, 7xi3_B
Binding Motifs: M0197_1.02 trtCACGTGrg
USF1_MOUSE.H10MO.A|M01405 gGTCACGTGr
Related annotations: PaperBLAST

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