Transcription Factor
| Accessions: | Q03060 (JASPAR 2024) |
| Names: | cAMP-responsive element modulator, CREM_HUMAN, ICER, Inducible cAMP early repressor |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q03060 |
| Length: | 345 |
| Pfam Domains: | 102-140 pKID domain 284-340 bZIP transcription factor 289-337 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 MTMETVESQHDGSITASLTESKSAHVQTQTGQNSIPALAQVSVAGSGTRRGSPAVTLVQL 60 61 PSGQTIHVQGVIQTPQPWVIQSSEIHTVQVAAIAETDESAESEGVIDSHKRREILSRRPS 120 121 YRKILNELSSDVPGVPKIEEERSEEEGTPPSIATMAVPTSIYQTSTGQYIAIAQGGTIQI 180 181 SNPGSDGVQGLQALTMTNSGAPPPGATIVQYAAQSADGTQQFFVPGSQVVVQDEETELAP 240 241 SHMAAATGDMPTYQIRAPTAALPQGVVMAASPGSLHSPQQLAEEATRKRELRLMKNREAA 300 301 KECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPKTDY |
| Interface Residues: | 292, 295, 296, 297, 299, 300, 303, 304 |
| 3D-footprint Homologues: | 1gd2_G, 7x5e_F, 4eot_A, 5t01_B, 1dh3_C, 5vpe_D |
| Binding Motifs: | MA0609.2 gcrgTGACGTCAcygc MA0609.3 gTGACGTCAc |
| Binding Sites: | MA0609.3.1 / MA0609.3.2 / MA0609.3.7 / MA0609.3.8 MA0609.3.10 / MA0609.3.9 MA0609.2.1 MA0609.2.10 MA0609.2.11 MA0609.2.12 MA0609.2.13 / MA0609.2.14 / MA0609.2.7 / MA0609.2.8 MA0609.2.15 / MA0609.2.9 MA0609.2.10 / MA0609.2.16 MA0609.2.11 / MA0609.2.17 MA0609.2.12 / MA0609.2.18 MA0609.2.13 / MA0609.2.19 MA0609.2.2 MA0609.2.14 / MA0609.2.20 MA0609.2.3 MA0609.2.4 MA0609.2.5 MA0609.2.6 MA0609.2.7 MA0609.2.8 MA0609.2.9 MA0609.2.15 MA0609.2.16 MA0609.2.17 MA0609.2.18 MA0609.2.19 MA0609.2.20 MA0609.3.11 MA0609.3.12 MA0609.3.13 MA0609.3.14 MA0609.3.15 MA0609.3.16 MA0609.3.17 MA0609.3.18 MA0609.3.19 MA0609.3.20 MA0609.3.3 MA0609.3.4 MA0609.3.5 MA0609.3.6 |
| Publications: | Martianov I, Choukrallah MA, Krebs A, Ye T, Legras S, Rijkers E, Van Ijcken W, Jost B, Sassone-Corsi P, Davidson I. Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells. BMC Genomics : (2010). [Pubmed] |
| Related annotations: | PaperBLAST |
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