Transcription Factor
| Accessions: | 5kea_A (3D-footprint 20231221) |
| Names: | Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4_MOUSE, Krueppel-like factor 4 |
| Organisms: | Mus musculus |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q60793 |
| Length: | 87 |
| Pfam Domains: | 4-28 C2H2-type zinc finger 4-28 Zinc finger, C2H2 type 20-42 Zinc-finger double domain 34-58 C2H2-type zinc finger 34-58 Zinc finger, C2H2 type 50-75 Zinc-finger double domain 64-86 C2H2-type zinc finger 64-86 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 TATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDDLTRHYRKHTG 60 61 HRPFQCQKCDRAFSRSDHLALHMKRHF |
| Interface Residues: | 16, 17, 18, 19, 20, 22, 23, 25, 26, 29, 46, 47, 48, 49, 50, 52, 53, 54, 57, 74, 75, 76, 77, 78, 79, 80, 81, 82, 85 |
| 3D-footprint Homologues: | 6ml4_A, 7n5w_A, 3uk3_C, 1tf3_A, 6jnm_A, 8cuc_F, 1tf6_A, 4x9j_A, 2i13_A, 1llm_D, 6blw_A, 5kkq_D, 8ssu_A, 1ubd_C, 6u9q_A, 5ei9_F, 1mey_C, 5kl3_A, 7ysf_A, 6wmi_A, 2kmk_A, 7w1m_H, 5und_A, 2gli_A, 1g2f_F, 7eyi_G, 8ssq_A, 5v3j_F, 8h9h_G, 7y3m_I, 6e94_A, 2lt7_A, 6a57_A, 2jpa_A, 5k5i_A, 7y3l_A, 2wbs_A, 5yel_A, 8gn3_A, 7txc_E, 2drp_D, 1f2i_J, 5k5l_F, 4m9v_C, 5yj3_D, 8gh6_A |
| Binding Motifs: | 5kea_A smCACGCCY |
| Binding Sites: | 5kea_B 5kea_C |
| Publications: | Hashimoto H, Wang D, Steves AN, Jin P, Blumenthal RM, Zhang X, Cheng X. Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Res 44:10177-10185 (2016). [Pubmed] |
| Related annotations: | PaperBLAST |
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