Transcription Factor
| Accessions: | UP00307A (UniPROBE 20160601) |
| Names: | Matalpha2, Not Available |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Not Av |
| Description: | Homeobox-domain protein that, with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATal... |
| Length: | 129 |
| Pfam Domains: | 54-107 Homeobox domain 66-104 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 TTTITVLLKEMRSIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENV 60 61 RILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLS 120 121 GEPLAKKKE |
| Interface Residues: | 49, 51, 52, 53, 54, 93, 94, 96, 97, 100, 101, 104, 105, 107, 108 |
| 3D-footprint Homologues: | 2lkx_A, 3d1n_M, 1mnm_C, 1k61_B, 1le8_B, 4j19_B, 2ld5_A, 2xsd_C, 7xrc_C, 1ig7_A, 7q3o_C, 5flv_I, 1nk2_P, 6fqq_E, 5zjt_E, 3a01_E, 1puf_B, 4xrm_B, 6es3_K, 3cmy_A, 1zq3_P, 1du0_A, 7psx_B, 4xrs_G, 6fqp_B, 2hdd_A, 2hos_A, 6m3d_C |
| Binding Motifs: | UP00307A_1 htdtwrAACAATAGwmytmc |
| Binding Sites: | AAAACAAT AAACAATA AAACAATG AAACAATT AACAATAG AACAATTG AATACAAT AATTGTCA AATTGTGA AATTGTTA AATTGTTC ACAATTGT AGACAATA ATAACAAT ATTGTTAA ATTGTTCA ATTGTTTA GAACAATA AATTGTAT ATTGTGTG |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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