Transcription Factor
| Accessions: | Q8N184 (JASPAR 2024) |
| Names: | ZN567_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8N184 |
| Length: | 647 |
| Pfam Domains: | 6-46 KRAB box 253-263 C2H2-type zinc finger 253-275 Zinc finger, C2H2 type 271-291 Zinc-finger double domain 281-303 C2H2-type zinc finger 281-303 C2H2-type zinc finger 281-303 Zinc finger, C2H2 type 299-318 Zinc-finger double domain 309-331 C2H2-type zinc finger 309-331 C2H2-type zinc finger 309-331 Zinc finger, C2H2 type 323-346 Zinc-finger double domain 337-359 Zinc finger, C2H2 type 351-375 Zinc-finger double domain 364-375 C2H2-type zinc finger 365-387 Zinc finger, C2H2 type 365-387 C2H2-type zinc finger 380-403 Zinc-finger double domain 393-415 C2H2-type zinc finger 393-415 Zinc finger, C2H2 type 393-415 C2H2-type zinc finger 407-431 Zinc-finger double domain 421-431 C2H2-type zinc finger 421-443 Zinc finger, C2H2 type 421-444 C2H2-type zinc finger 438-459 Zinc-finger double domain 449-471 C2H2-type zinc finger 449-471 Zinc finger, C2H2 type 449-471 C2H2-type zinc finger 464-486 Zinc-finger double domain 477-496 C2H2-type zinc finger 477-499 Zinc finger, C2H2 type 477-499 C2H2-type zinc finger 495-515 Zinc-finger double domain 504-515 C2H2-type zinc finger 505-527 C2H2-type zinc finger 505-527 Zinc finger, C2H2 type 519-543 Zinc-finger double domain 533-555 C2H2-type zinc finger 533-551 C2H2-type zinc finger 533-555 Zinc finger, C2H2 type 548-572 Zinc-finger double domain 561-583 Zinc finger, C2H2 type 561-583 C2H2-type zinc finger 561-583 C2H2-type zinc finger 579-599 Zinc-finger double domain 588-611 C2H2-type zinc finger 589-611 Zinc finger, C2H2 type 589-611 C2H2-type zinc finger 603-628 Zinc-finger double domain 617-640 C2H2-type zinc finger 617-639 Zinc finger, C2H2 type 617-639 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MAQGSVSFNDVTVDFTQEEWQHLDHAQKTLYMDVMLENYCHLISVGCHMTKPDVILKLER 60 61 GEEPWTSFAGHTCLEENWKAEDFLVKFKEHQEKYSRSVVSINHKKLVKEKSKIYEKTFTL 120 121 GKNPVNSKNLPPEYDTHGRILKNVSELIISNLNPARKRLSEYNGYGKSLLSTKQETTHPE 180 181 VKSHNQSARAFSHNEVLMQYQKTETPAQSFGYNDCEKSFLQRGGLITHSRPYKGENPSVY 240 241 NKKRRATNIEKKHTCNECGKSFCRKSVLILHQGIHSEEKPYQCHQCGNAFRRKSYLIDHQ 300 301 RTHTGEKPFVCNECGKSFRLKTALTDHQRTHTGEKSYECLQCRNAFRLKSHLIRHQRTHT 360 361 GEKPYECNDCGKSFRQKTTLSLHQRIHTGEKPYICKECGKSFHQKANLTVHQRTHTGEKP 420 421 YICNECGKSFSQKTTLALHEKTHNEEKPYICSECGKSFRQKTTLVAHQRTHTGEKSYECP 480 481 HCGKAFRMKSYLIDHHRTHTGEKPYECNECGKSFSQKTNLNLHQRIHTGEKPYVCNECGK 540 541 SFRQKATLTVHQKIHTGQKSYECPQCGKAFSRKSYLIHHQRTHTGEKPYKCSECGKCFRQ 600 601 KTNLIVHQRTHTGEKPYVCNECGKSFSYKRNLIVHQRTHKGENIEMQ |
| Interface Residues: | 292, 294, 295, 298, 319, 320, 322, 323, 324, 326, 327, 330, 347, 348, 349, 350, 351, 353, 354, 356, 357, 360, 365, 375, 376, 377, 378, 379, 382, 403, 404, 405, 406, 407, 409, 410, 431, 432, 433, 434, 435, 438, 441, 460, 461, 462, 463, 465, 466, 469, 487, 488, 489, 490, 491, 493, 494, 500, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 526, 543, 544, 545, 546, 547, 548, 549, 550, 551, 571, 572, 574, 575, 577, 578, 599, 600, 602, 603, 606, 628, 629, 630, 631, 633, 634, 638 |
| 3D-footprint Homologues: | 1llm_D, 8ssq_A, 7w1m_H, 5kkq_D, 6blw_A, 5v3j_F, 2jpa_A, 1ubd_C, 2kmk_A, 1tf3_A, 5kl3_A, 4x9j_A, 2gli_A, 1tf6_A, 1g2f_F, 6e94_A, 6u9q_A, 2wbs_A, 5yel_A, 8ssu_A, 7ysf_A, 2lt7_A, 3uk3_C, 7n5w_A, 6ml4_A, 2drp_D, 8gn3_A, 8h9h_G, 5k5i_A, 4m9v_C, 7txc_E, 1f2i_J, 5ei9_F, 6jnm_A, 5k5l_F, 5yj3_D, 6a57_A, 8cuc_F, 7y3l_A, 7y3m_I |
| Binding Motifs: | UN0633.1 atArAAryAGACCCAsAra |
| Binding Sites: | UN0633.1.1 / UN0633.1.6 UN0633.1.10 UN0633.1.11 UN0633.1.12 UN0633.1.13 UN0633.1.14 UN0633.1.15 UN0633.1.16 UN0633.1.17 UN0633.1.18 UN0633.1.19 UN0633.1.2 / UN0633.1.7 UN0633.1.20 UN0633.1.3 / UN0633.1.8 UN0633.1.4 / UN0633.1.9 UN0633.1.10 / UN0633.1.5 UN0633.1.13 / UN0633.1.6 UN0633.1.14 / UN0633.1.7 UN0633.1.15 / UN0633.1.8 UN0633.1.9 UN0633.1.1 UN0633.1.11 UN0633.1.12 UN0633.1.16 UN0633.1.17 UN0633.1.18 UN0633.1.19 UN0633.1.2 UN0633.1.20 UN0633.1.3 UN0633.1.4 UN0633.1.5 |
| Related annotations: | PaperBLAST |
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