Transcription Factor

Accessions: 2ql2_B (3D-footprint 20241219)
Names: Beta-cell E-box transcriptional activator 2, Beta2, NDF1_MOUSE, NeuroD1, Neurogenic differentiation factor 1
Organisms: Mus musculus
Libraries: 3D-footprint 20241219 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q60867
Length: 59
Pfam Domains: 2-53 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 SRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRS
Interface Residues: 3, 7, 9, 10, 13
3D-footprint Homologues: 7z5k_B, 8osb_B
Binding Motifs: 2ql2_AB cCAnnTGg
Binding Sites: 2ql2_E
2ql2_F
Publications: Longo A, Guanga G.P, Rose R.B. Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition. Biochemistry 47:218-29 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.