Transcription Factor
| Accessions: | Q12772 (JASPAR 2024) |
| Names: | bHLHd2, Class D basic helix-loop-helix protein 2, SRBP2_HUMAN, SREBP-2, Sterol regulatory element-binding protein 2, Sterol regulatory element-binding transcription factor 2, Transcription factor SREBF2 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q12772 |
| Length: | |
| Binding Motifs: | MA0828.1 ATCACGTGAy MA0596.1 rTGGgGTGAy MA1933.1 rcCGGAAGTsrCGTGA MA1939.1 ssCGGAArTCACGTGAy MA0828.2 wtrTCACGTGAyaw MA0828.3 rTCACGTGAy MA1933.2 cCGGAAGTsrCGTGA MA1939.2 sCGGAArTCACGTGAy |
| Binding Sites: | MA0596.1.1 MA0596.1.10 MA0596.1.11 MA0596.1.12 MA0596.1.13 MA0596.1.14 MA0596.1.15 MA0596.1.16 MA0596.1.17 MA0596.1.18 MA0596.1.19 MA0596.1.2 MA0596.1.20 MA0596.1.3 MA0596.1.4 MA0596.1.5 MA0596.1.6 MA0596.1.7 MA0596.1.8 MA0596.1.9 |
| Publications: | Wang X., Sato R. R., Brown M. S., Hua X., Goldstein J. L. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell 77:53-62 (1994). [Pubmed] Shimano H. Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes. Prog Lipid Res 40:439-52 (2001). [Pubmed] Chatterjee R, Zhao J, He X, Shlyakhtenko A, Mann I, Waterfall JJ, Meltzer P, Sathyanarayana BK, FitzGerald PC, Vinson C. Overlapping ETS and CRE Motifs ((G/C)CGGAAGTGACGTCA) preferentially bound by GABPα and CREB proteins. G3 (Bethesda) 2:1243-56 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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