Transcription Factor
| Accessions: | Ubx (DrosophilaTF 1.1), P83949 (JASPAR 2024) |
| Names: | UBX_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 389 |
| Pfam Domains: | 296-352 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MNSYFEQASGFYGHPHQATGMAMGSGGHHDQTASAAAAAYRGFPLSLGMSPYANHHLQRT 60 61 TQDSPYDASITAACNKIYGDGAGAYKQDCLNIKADAVNGYKDIWNTGGSNGGGGGGGGGG 120 121 GGGAGGTGGAGNANGGNAANANGQNNPAGGMPVRPSACTPDSRVGGYLDTSGGSPVSHRG 180 181 GSAGGNVSVSGGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQASNHTFY 240 241 PWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQ 300 301 TYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKEL 360 361 NEQEKQAQAQKAAAAAAAAAAVQGGHLDQ |
| Interface Residues: | 295, 296, 297, 298, 299, 300, 322, 326, 329, 330, 333, 337, 338, 340, 341, 344, 345, 348, 349, 352 |
| 3D-footprint Homologues: | 4j19_B, 1puf_A, 3a01_E, 1ig7_A, 2h1k_B, 6a8r_A, 1fjl_B, 3cmy_A, 5zfz_A, 1zq3_P, 6m3d_C, 3d1n_M, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 2ld5_A, 5flv_I, 5zjt_E, 7psx_B, 5hod_A, 2hdd_A, 7q3o_C, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 6es3_K, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 2wt7_A, 2xsd_C, 1e3o_C, 1le8_A, 1au7_A, 7xrc_C, 1o4x_A, 1du0_A, 4qtr_D |
| Binding Motifs: | MA0094.2 yTTAATKR Ubx kdrgrstTAATkGsytygk MA0094.1 TAAT MA0094.3 TTAATKR |
| Binding Sites: | Ubx_1 Ubx_2 Ubx_5 Ubx_10 Ubx_11 Ubx_12 Ubx_16 Ubx_20 Ubx_24 Ubx_27 Ubx_28 Ubx_31 Ubx_33 Ubx_36 Ubx_39 Ubx_40 Ubx_44 Ubx_49 Ubx_56 Ubx_58 Ubx_65 Ubx_70 Ubx_72 Ubx_75 Ubx_81 Ubx_86 Ubx_88 Ubx_13 Ubx_14 Ubx_15 Ubx_17 Ubx_18 Ubx_19 Ubx_21 Ubx_22 Ubx_23 Ubx_25 Ubx_26 Ubx_29 Ubx_3 Ubx_30 Ubx_32 Ubx_34 Ubx_35 Ubx_37 Ubx_38 Ubx_4 Ubx_41 Ubx_42 Ubx_43 Ubx_45 Ubx_46 Ubx_47 Ubx_48 Ubx_50 Ubx_51 Ubx_52 Ubx_53 Ubx_54 Ubx_55 Ubx_57 Ubx_59 Ubx_6 Ubx_60 Ubx_61 Ubx_62 / Ubx_63 Ubx_64 Ubx_66 Ubx_67 Ubx_68 Ubx_69 / Ubx_71 Ubx_7 Ubx_73 Ubx_74 Ubx_76 Ubx_77 Ubx_78 Ubx_79 Ubx_8 Ubx_80 Ubx_82 Ubx_83 Ubx_84 Ubx_85 Ubx_87 Ubx_9 MA0094.1.1 MA0094.1.10 / MA0094.1.8 MA0094.1.11 MA0094.1.12 MA0094.1.13 MA0094.1.14 MA0094.1.15 / MA0094.1.5 MA0094.1.16 MA0094.1.17 MA0094.1.18 MA0094.1.19 MA0094.1.2 MA0094.1.20 MA0094.1.3 MA0094.1.4 MA0094.1.6 MA0094.1.7 MA0094.1.9 MA0094.2.1 MA0094.2.10 MA0094.2.11 MA0094.2.12 / MA0094.2.17 MA0094.2.13 MA0094.2.14 MA0094.2.15 MA0094.2.16 MA0094.2.18 MA0094.2.19 MA0094.2.2 MA0094.2.20 MA0094.2.3 / MA0094.2.4 MA0094.2.5 MA0094.2.6 MA0094.2.7 MA0094.2.8 MA0094.2.9 MA0094.3.13 / MA0094.3.20 / MA0094.3.7 MA0094.3.1 MA0094.3.10 MA0094.3.11 / MA0094.3.14 MA0094.3.12 / MA0094.3.16 / MA0094.3.17 MA0094.3.15 MA0094.3.18 MA0094.3.19 MA0094.3.2 MA0094.3.3 / MA0094.3.4 MA0094.3.5 / MA0094.3.8 MA0094.3.6 MA0094.3.9 |
| Publications: | Ekker S. C., Young K. E., von Kessler D. P., Beachy P. A. Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila. EMBO J. 10:1179-1186 (1991). [Pubmed] Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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