Transcription Factor
| Accessions: | Q9UIH9 (JASPAR 2024) |
| Names: | Kidney-enriched krueppel-like factor, KLF15_HUMAN, Krueppel-like factor 15 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 416 |
| Pfam Domains: | 321-345 C2H2-type zinc finger 321-345 Zinc finger, C2H2 type 337-359 Zinc-finger double domain 351-375 C2H2-type zinc finger 351-375 Zinc finger, C2H2 type 368-391 Zinc-finger double domain 381-403 Zinc finger, C2H2 type 381-403 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MVDHLLPVDENFSSPKCPVGYLGDRLVGRRAYHMLPSPVSEDDSDASSPCSCSSPDSQAL 60 61 CSCYGGGLGTESQDSILDFLLSQATLGSGGGSGSSIGASSGPVAWGPWRRAAAPVKGEHF 120 121 CLPEFPLGDPDDVPRPFQPTLEEIEEFLEENMEPGVKEVPEGNSKDLDACSQLSAGPHKS 180 181 HLHPGSSGRERCSPPPGGASAGGAQGPGGGPTPDGPIPVLLQIQPVPVKQESGTGPASPG 240 241 QAPENVKVAQLLVNIQGQTFALVPQVVPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGP 300 301 AGLLMGQKFPKNPAAELIKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGW 360 361 RFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSSRSVRSVN |
| Interface Residues: | 34, 35, 267, 268, 270, 271, 275, 305, 308, 311, 333, 334, 335, 336, 337, 339, 340, 342, 343, 346, 361, 363, 364, 365, 366, 367, 369, 370, 371, 374, 391, 392, 393, 394, 395, 396, 397, 398, 399 |
| 3D-footprint Homologues: | 4glx_A, 5v3j_F, 8cuc_F, 7y3l_A, 6ml4_A, 7n5w_A, 1tf3_A, 6jnm_A, 2gli_A, 1g2f_F, 7eyi_G, 5k5i_A, 1tf6_A, 2i13_A, 1llm_D, 6blw_A, 1ubd_C, 6u9q_A, 4x9j_A, 1mey_C, 5kl3_A, 7ysf_A, 6wmi_A, 5ei9_F, 2kmk_A, 8h9h_G, 2lt7_A, 8ssu_A, 5kkq_D, 7y3m_I, 6e94_A, 8ssq_A, 7w1m_H, 5und_A, 6a57_A, 2jpa_A, 3uk3_C, 8gn3_A, 2wbs_A, 5yel_A, 7txc_E, 2drp_D, 1f2i_J, 5yj3_D, 4m9v_C |
| Binding Motifs: | MA1513.1 scCCCGCCCcs MA1513.2 cCCCGCCC |
| Binding Sites: | MA1513.2.11 / MA1513.2.13 / MA1513.2.18 / MA1513.2.20 MA1513.2.17 MA1513.2.1 / MA1513.2.10 / MA1513.2.12 / MA1513.2.2 / MA1513.2.3 / MA1513.2.4 / MA1513.2.5 / MA1513.2.6 / MA1513.2.7 / MA1513.2.8 MA1513.1.1 MA1513.1.10 MA1513.1.10 / MA1513.1.11 MA1513.1.11 / MA1513.1.12 MA1513.1.12 / MA1513.1.13 MA1513.1.13 / MA1513.1.14 MA1513.1.14 / MA1513.1.15 MA1513.1.15 / MA1513.1.16 MA1513.1.16 / MA1513.1.17 MA1513.1.18 MA1513.1.17 / MA1513.1.19 MA1513.1.2 MA1513.1.18 / MA1513.1.20 MA1513.1.2 / MA1513.1.3 MA1513.1.3 / MA1513.1.4 MA1513.1.4 / MA1513.1.5 MA1513.1.5 / MA1513.1.6 MA1513.1.6 / MA1513.1.7 MA1513.1.7 / MA1513.1.8 MA1513.1.8 / MA1513.1.9 MA1513.1.19 MA1513.1.20 MA1513.1.9 MA1513.2.14 / MA1513.2.15 / MA1513.2.16 MA1513.2.19 MA1513.2.9 |
| Publications: | Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Related annotations: | PaperBLAST |
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