Transcription Factor

Accessions: 5edn_G (3D-footprint 20231221)
Names: Homeobox protein Hox-B13, HXB13_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q92826
Length: 60
Pfam Domains: 1-56 Homeobox domain
Sequence:
(in bold interface residues)
1 KKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAK 60
Interface Residues: 1, 2, 3, 11, 27, 29, 41, 42, 44, 45, 48, 49, 52, 53, 56
3D-footprint Homologues: 1nk2_P, 1zq3_P, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 3cmy_A, 2hdd_A, 7psx_B, 6a8r_A, 2r5y_A, 6m3d_C, 1au7_A, 5jlw_D, 3lnq_A, 2hos_A, 1fjl_B, 4xrs_G, 1b72_A, 5zfz_A, 3rkq_B, 1ig7_A, 5flv_I, 3a01_E, 2h1k_B, 5zjt_E, 4cyc_A, 1puf_A, 1jgg_B, 6vu3_A, 6vz3_A, 1e3o_C, 2xsd_C, 1le8_A, 7xrc_C, 5hod_A, 1mnm_C, 4qtr_D, 1puf_B, 1k61_B, 1o4x_A, 6fqp_B, 1le8_B, 1du0_A, 6fqq_E
Binding Motifs: 5edn_BG gnnnnnGTAAAnnnnnGnnnnnntnaCTAG
Binding Sites: 5edn_D
5edn_E
Publications: Morgunova E, Yin Y, Das PK, Jolma A, Zhu F, Popov A, Xu Y, Nilsson L, Taipale J. Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife : (2018). [Pubmed]
Related annotations: PaperBLAST

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