Transcription Factor

						

			
Accessions: T049154_1.02 (CISBP 1.02)

			
Names: T049154_1.02;, Zfp300
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 645
Pfam Domains:      7-47 KRAB box
  257-280 Zinc-finger double domain
  270-290 C2H2-type zinc finger
  271-293 Zinc finger, C2H2 type
  271-293 C2H2-type zinc finger
  289-308 Zinc-finger double domain
  299-322 C2H2-type zinc finger
  299-321 Zinc finger, C2H2 type
  313-337 Zinc-finger double domain
  326-337 C2H2-type zinc finger
  327-349 Zinc finger, C2H2 type
  327-349 C2H2-type zinc finger
  341-364 Zinc-finger double domain
  355-377 Zinc finger, C2H2 type
  355-377 C2H2-type zinc finger
  370-392 Zinc-finger double domain
  383-405 C2H2-type zinc finger
  383-405 C2H2-type zinc finger
  383-405 Zinc finger, C2H2 type
  400-421 Zinc-finger double domain
  410-421 C2H2-type zinc finger
  411-433 Zinc finger, C2H2 type
  411-433 C2H2-type zinc finger
  425-448 Zinc-finger double domain
  439-461 Zinc finger, C2H2 type
  439-461 C2H2-type zinc finger
  439-459 C2H2-type zinc finger
  454-477 Zinc-finger double domain
  467-489 Zinc finger, C2H2 type
  467-489 C2H2-type zinc finger
  467-477 C2H2-type zinc finger
  481-506 Zinc-finger double domain
  497-517 Zinc finger, C2H2 type
  497-517 C2H2-type zinc finger
  497-506 C2H2-type zinc finger
  510-536 Zinc-finger double domain
  526-538 C2H2-type zinc finger
  526-548 Zinc finger, C2H2 type
  526-548 C2H2-type zinc finger
  543-564 Zinc-finger double domain
  553-564 C2H2-type zinc finger
  554-576 Zinc finger, C2H2 type
  554-576 C2H2-type zinc finger
  571-591 Zinc-finger double domain
  582-604 C2H2-type zinc finger
  582-604 Zinc finger, C2H2 type
  582-604 C2H2-type zinc finger
  597-613 Zinc-finger double domain
Sequence: 
(in bold interface residues)		   1 MQLQESVSFEDVSVDFTQEEWNQLDPIQRSLYRDVMLENYSHLVSLGYPITKPEVIASLE   60
  61 KGVLGIIKREIPSSSCTEDGQAEYNLAWHQKNQNMHLEQAISIIEKNVTEERSYEYDGFV  120
 121 SPLSQSTWVVSSGPTPYMNNSFGESIKNNLGLVNPSSMSFAAQECYECNRCRKLLIPGRH  180
 181 EISDRMKSQEHNMFGKEHIYNFVQHDLTQLGDKTYECPECRITLSPSSFLVVHQITHIGE  240
 241 KPYEWARCREAFNNTAHLSLHQTMHTGDKLFECNECGKSFREESTLHIHQRTHTGEKPYI  300
 301 CTECGNAFQEKTNLIIHRRTHKGEKPYKCTDCEKTFNQKAHLNVHQRTHTGEKPFECTNC  360
 361 GKYFREKSTLNIHQRTHTGEKPYVCNECGKAFREKTKLIIHQRTHTGEKPYECSECGRAF  420
 421 NQKAHLSVHQRTHTGEKPFECNECGKAFREKSTLRRHQRIHTGEKPYVCSECGRAFTLKL  480
 481 SLSAHQRIHTGEKTDGCTVCGKVFSRKSYLMLHQRAHTKERLEKSYECNECDKAFLQKSY  540
 541 LIIHQRVHAGEKPYECNICEKSFSQKSYLIIHQRIHTGEKPYQCDKCSRAFREKSKLTVH  600
 601 QRTHIGEKPYDCPELERNFPEIKVPHGLENSEMKENKELKMENLS
Interface Residues: 254, 257, 260, 264, 282, 284, 285, 288, 310, 311, 312, 313, 315, 316, 320, 337, 338, 339, 340, 341, 344, 355, 365, 366, 367, 368, 369, 371, 372, 374, 375, 378, 393, 394, 395, 396, 397, 399, 400, 421, 422, 423, 424, 425, 427, 428, 449, 450, 451, 452, 453, 454, 455, 456, 457, 459, 477, 478, 479, 480, 481, 482, 483, 484, 485, 506, 507, 508, 509, 512, 515, 536, 539, 540, 549, 563, 565, 566, 567, 568, 571, 575, 592, 593, 594, 595, 596, 598, 599
3D-footprint Homologues: 8ssq_A, 5v3j_F, 7y3m_I, 1tf6_A, 5k5i_A, 2lt7_A, 7n5w_A, 7w1m_H, 5kkq_D, 5kl3_A, 8h9h_G, 5yel_A, 2kmk_A, 8cuc_F, 3uk3_C, 6blw_A, 5k5l_F, 2jpa_A, 1ubd_C, 1tf3_A, 7y3l_A, 6ml4_A, 6u9q_A, 4x9j_A, 2gli_A, 8ssu_A, 2wbs_A, 5ei9_F, 1g2f_F, 7ysf_A, 5yj3_D, 1llm_D, 6e94_A, 8gn3_A, 7txc_E, 4m9v_C, 6jnm_A, 6a57_A, 2drp_D, 1f2i_J
Binding Motifs: M0411_1.02 astwrTGtaTamkwa
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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