Transcription Factor
| Accessions: | ERF2 (Athamap 20091028), T000696_1.02 (CISBP 1.02), O80338 (JASPAR 2024), T21847 (AthalianaCistrome v4_May2016) |
| Names: | AtERF2, EREBP-2, ERF2, Ethylene-responsive element-binding factor 2, Ethylene-responsive transcription factor 2, T000696_1.02;, EF101_ARATH, AT5G47220, T21847; |
| Organisms: | Arabidopsis thaliana |
| Libraries: | Athamap 20091028 1, CISBP 1.02 2, JASPAR 2024 3, AthalianaCistrome v4_May2016 4 1 Bulow L, Engelmann S, Schindler M, Hehl R. AthaMap, integrating transcriptional and post-transcriptional data. Nucleic acids research 37:D983-6 (2009). [Pubmed] 2 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 4 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Notes: | experiment type:PBM, family:AP2, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:AP2-EREBP |
| Length: | 243 |
| Pfam Domains: | 116-166 AP2 domain |
| Sequence: (in bold interface residues) | 1 MYGQCNIESDYALLESITRHLLGGGGENELRLNESTPSSCFTESWGGLPLKENDSEDMLV 60 61 YGLLKDAFHFDTSSSDLSCLFDFPAVKVEPTENFTAMEEKPKKAIPVTETAVKAKHYRGV 120 121 RQRPWGKFAAEIRDPAKNGARVWLGTFETAEDAALAYDIAAFRMRGSRALLNFPLRVNSG 180 181 EPDPVRITSKRSSSSSSSSSSSTSSSENGKLKRRRKAENLTSEVVQVKCEVGDETRVDEL 240 241 LVS |
| Interface Residues: | 121, 123, 124, 125, 129, 131, 133, 136, 141, 143 |
| 3D-footprint Homologues: | 7wq5_A, 1gcc_A, 5wx9_A, 7et4_D |
| Binding Motifs: | ERF2 AGCCGCCA M0038_1.02 hsmGCCGcCa M0109 / MA1262.1 ccdccrccdcCGCCGCCrycr M0093 cckccgccrcckcCGCCGCCr MA1262.2 ccdcCGCCGCCry |
| Binding Sites: | ERF2_1 ERF2_2 MA1262.1.6 MA1262.1.7 MA1262.1.5 MA1262.1.10 MA1262.1.1 MA1262.1.11 MA1262.1.12 MA1262.1.13 MA1262.1.14 MA1262.1.15 MA1262.1.16 MA1262.1.17 MA1262.1.18 MA1262.1.19 MA1262.1.2 MA1262.1.20 MA1262.1.3 MA1262.1.4 MA1262.1.8 MA1262.1.9 MA1262.2.1 MA1262.2.10 MA1262.2.11 MA1262.2.12 MA1262.2.13 MA1262.2.14 MA1262.2.15 MA1262.2.16 MA1262.2.17 MA1262.2.18 MA1262.2.19 MA1262.2.2 MA1262.2.20 MA1262.2.3 MA1262.2.4 MA1262.2.5 MA1262.2.6 MA1262.2.7 MA1262.2.8 MA1262.2.9 |
| Publications: | Fujimoto SY, Ohta M, Usui A, Shinshi H, Ohme-Takagi M. 2000. Arabidopsis ethylene-responsive element binding factors act as transcriptional activators or repressors of GCC box-mediated gene expression. Plant Cell. 12:393-404. [Pubmed] Hao D., Ohme-Takagi M., Sarai A. Unique mode of GCC box recognition by the DNA-binding domain of ethylene-responsive element-binding factor (ERF domain) in plant. J. Biol. Chem. 273:26857-26861 (1998). [Pubmed] |
| Related annotations: | PaperBLAST |
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