Transcription Factor

Accessions: 1hwt_H (3D-footprint 20231221)
Names: CYP1 activatory protein, HAP1_YEASX, HEME ACTIVATOR PROTEIN, Heme activator protein 1, Heme-responsive zinc finger transcription factor HAP1
Organisms: Saccharomyces cerevisiae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0CS82
Length: 73
Pfam Domains: 8-42 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence:
(in bold interface residues)
1 KRNRIPLSCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNELK 60
61 KLRERVKSLEKTL
Interface Residues: 15, 16, 17, 18, 20, 21
3D-footprint Homologues: 1hwt_C, 1pyi_A, 6o19_A, 1zme_D, 1d66_B, 3coq_A, 7uik_T, 6gys_C, 7n5w_A, 8h9h_G
Binding Motifs: 1hwt_GH GCGATAatnGCG
Binding Sites: 1hwt_E
1hwt_F
Publications: King D.A, Zhang L, Guarente L, Marmorstein R. Structure of a HAP1-DNA complex reveals dramatically asymmetric DNA binding by a homodimeric protein. Nature structural biology 6:64-71 (1999). [Pubmed]
Related annotations: PaperBLAST

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