Transcription Factor
| Accessions: | Q6AHZ1 (JASPAR 2024) |
| Names: | Z518A_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q6AHZ1 |
| Length: | 1483 |
| Pfam Domains: | 134-158 Zinc-finger double domain 249-272 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MPSEQKQLFCDEKQTTLKKDYDVKNEIVDRSAPKPKISGSIHYALKNVKIDLPKINIPNE 60 61 VLLKHEVDKYRKLFQSKQQTARKSISIKTVSCVEECTLLHKSERAEEEGVKMSAKILNFS 120 121 CLKCRDNTRYSPNDLQKHFQMWHHGELPSYPCEMCNFSANDFQVFKQHRRTHRSTLVKCD 180 181 ICNNESVYTLLNLTKHFTSTHCVNGNFQCEKCKFSTQDVGTFVQHIHRHNEIHYKCGKCH 240 241 HVCFTKGELQKHLHIHSGTFPFTCQYCSYGATRREHLVRHVITLHKEHLYAKEKLEKDKY 300 301 EKRMAKTSAGLKLILKRYKIGASRKTFWKRKKINSGSDRSIEKNTQVLKKMNKTQTKSED 360 361 QSHVVQEHLSEEKDERLHCENNDKAPESESEKPTPLSTGQGNRAEEGPNASSGFMKTAVL 420 421 GPTLKNVMMKNNKLAVSPNYNATFMGFKMMDGKQHIVLKLVPIKQNVCSPGSQSGAAKDG 480 481 TANLQPQTLDTNGFLTGVTTELNDTVYMKAATPFSCSSSILSGKASSEKEMTLISQRNNM 540 541 LQTMDYEKSVSSLSATSELVTASVNLTTKFETRDNVDFWGNHLTQSHPEVLGTTIKSPDK 600 601 VNCVAKPNAYNSGDMHNYCINYGNCELPVESSNQGSLPFHNYSKVNNSNKRRRFSGTAVY 660 661 ENPQRESSSSKTVVQQPISESFLSLVRQESSKPDSLLASISLLNDKDGTLKAKSEIEEQY 720 721 VLEKGQNIDGQNLYSNENQNLECATEKSKWEDFSNVDSPMMPRITSVFSLQSQQASEFLP 780 781 PEVNQLLQDVLKIKPDVKQDSSNTPNKGLPLHCDQSFQKHEREGKIVESSKDFKVQGIFP 840 841 VPPGSVGINVPTNDLNLKFGKEKQVSSIPQDVRDSEKMPRISGFGTLLKTQSDAIITQQL 900 901 VKDKLRATTQNLGSFYMQSPLLNSEQKKTIIVQTSKGFLIPLNITNKPGLPVIPGNALPL 960 961 VNSQGIPASLFVNKKPGMVLTLNNGKLEGVSAVKTEGAPARGTVTKEPCKTPILKVEPNN 1020 1021 NCLTPGLCSSIGSCLSMKSSSENTLPLKGPYILKPTSSVKAVLIPNMLSEQQSTKLNISD 1080 1081 SVKQQNEIFPKPPLYTFLPDGKQAVFLKCVMPNKTELLKPKLVQNSTYQNIQPKKPEGTP 1140 1141 QRILLKIFNPVLNVTAANNLSVSNSASSLQKDNVPSNQIIGGEQKEPESRDALPFLLDDL 1200 1201 MPANEIVITSTATCPESSEEPICVSDCSESRVLRCKTNCRIERNFNRKKTSKKIFSKTKT 1260 1261 HGSKDSETAFVSRNRNCKRKCRDSYQEPPRRKATLHRKCKEKAKPEDVRETFGFSRPRLS 1320 1321 KDSIRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADAPEVVSVMKTIAKFNGHVLKVSLS 1380 1381 KRTINALLKPVCYNPPKTTYDDFSKRHKTFKPVSSVKERFVLKLTLKKTSKNNYQIVKTT 1440 1441 SENILKAKFNCWFCGRVFDNQDTWAGHGQRHLMEATRDWNMLE |
| Interface Residues: | 131, 133, 134, 137, 158, 160, 161, 162, 163, 164, 167, 189, 190, 191, 192, 193, 195, 199, 207, 215, 216, 217, 218, 219, 220, 221, 223, 224, 225, 228, 229, 244, 245, 246, 247, 248, 249, 250, 251, 272, 273, 274, 275, 276, 278, 279, 301, 303, 304 |
| 3D-footprint Homologues: | 5v3j_F, 8ssq_A, 8ssu_A, 5und_A, 5yel_A, 6u9q_A, 7w1m_H, 2i13_A, 5kkq_D, 6ml4_A, 7eyi_G, 7ysf_A, 2kmk_A, 5kl3_A, 7n5w_A, 5ei9_F, 1mey_C, 8h9h_G, 6e94_A, 3uk3_C, 7txc_E, 8gn3_A, 2lt7_A, 7y3m_I, 1g2f_F, 6blw_A, 2wbs_A, 2jpa_A, 1tf3_A, 1f2i_J, 4x9j_A, 1tf6_A, 5yj3_D |
| Binding Motifs: | UN0199.1 TAAATAAATA |
| Binding Sites: | UN0199.1.1 UN0199.1.10 UN0199.1.11 UN0199.1.12 UN0199.1.13 UN0199.1.14 / UN0199.1.9 UN0199.1.15 UN0199.1.11 / UN0199.1.16 UN0199.1.17 UN0199.1.14 / UN0199.1.18 UN0199.1.19 UN0199.1.2 UN0199.1.20 UN0199.1.3 / UN0199.1.6 UN0199.1.4 UN0199.1.5 UN0199.1.6 UN0199.1.7 UN0199.1.8 UN0199.1.9 UN0199.1.1 UN0199.1.10 UN0199.1.12 UN0199.1.13 UN0199.1.15 UN0199.1.16 UN0199.1.17 UN0199.1.18 UN0199.1.19 UN0199.1.2 UN0199.1.20 UN0199.1.3 UN0199.1.4 UN0199.1.5 UN0199.1.7 UN0199.1.8 |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.