Transcription Factor

						

			
Accessions: 4atk_B (3D-footprint 20231221)

			
Names: MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR, MITF_MOUSE
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q08874
Length: 60
Pfam Domains:      1-54 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 KKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRA   60
Interface Residues: 2, 5, 6, 8, 9, 10, 12, 13, 37, 39
3D-footprint Homologues: 1a0a_B, 5eyo_A, 7f2f_B, 5nj8_D, 4h10_A, 7xi3_A, 6g1l_A, 5gnj_I, 7rcu_E, 5sy7_B, 4h10_B, 5i50_B, 7ssa_L, 5v0l_A, 4zpk_A, 1am9_A, 8osl_O, 7d8t_A, 8osl_P, 1an4_A, 6od3_F, 2ypa_A, 5nj8_C, 2ypa_B, 7xhv_B, 5v0l_B, 7xi3_B, 2vs7_A
Binding Motifs: 4atk_AB AGCACGTGC
4atk_B CGTGc
Binding Sites: 4atk_C / 4atk_D
			
Publications: Pogenberg V, Ogmundsdóttir M.H, Bergsteinsdóttir K, Schepsky A, Phung B, Deineko V, Milewski M, Steingrímsson E, Wilmanns M. Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF. Genes & development 26:2647-58 (2012). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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