Transcription Factor

						

			
Accessions: 4l18_E (3D-footprint 20231221)

			
Names: Acute myeloid leukemia 1 protein, CBF-alpha-2, Core-binding factor subunit alpha-2, Oncogene AML-1, PEA2-alpha B, PEBP2-alpha B, Polyomavirus enhancer-binding protein 2 alpha B subunit, Runt-related transcription factor 1, RUNX1_MOUSE, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q03347
Length: 141
Pfam Domains:     2-127 Runt domain
Sequence: 
(in bold interface residues)		   1 VEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDE   60
  61 NYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVD  120
 121 GPREPRGSLSFSERLSELEQL
Interface Residues: 29, 91, 119, 120, 123, 126
3D-footprint Homologues: 4l0y_A, 4l18_E, 6vg8_D, 3wts_A, 6vgd_D
Binding Motifs: 4l18_E AAGCCACA
4l18_EF AGGATGTGGCTT
Binding Sites: 4l18_G
4l18_H
			
Publications: Shrivastava T, Mino K, Babayeva N.D, Baranovskaya O.I, Rizzino A, Tahirov T.H. Structural basis of Ets1 activation by Runx1. Leukemia 28:2040-8 (2014). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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