Transcription Factor
| Accessions: | Q8IWY8 (JASPAR 2024) |
| Names: | Zinc finger and SCAN domain-containing protein 29, Zinc finger protein 690, ZSC29_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8IWY8 |
| Length: | 852 |
| Pfam Domains: | 13-106 SCAN domain 246-330 Myb/SANT-like DNA-binding domain 409-493 Myb/SANT-like DNA-binding domain 665-689 Zinc-finger double domain 677-698 C2H2-type zinc finger 678-700 C2H2-type zinc finger 678-700 Zinc finger, C2H2 type 693-715 Zinc-finger double domain 705-726 C2H2-type zinc finger 706-728 Zinc finger, C2H2 type 723-744 Zinc-finger double domain 734-756 C2H2-type zinc finger 734-756 C2H2-type zinc finger 734-756 Zinc finger, C2H2 type 750-773 Zinc-finger double domain 762-784 Zinc finger, C2H2 type 762-782 C2H2-type zinc finger 762-784 C2H2-type zinc finger 777-800 Zinc-finger double domain 789-812 C2H2-type zinc finger 790-812 Zinc finger, C2H2 type 790-812 C2H2-type zinc finger 804-828 Zinc-finger double domain 818-840 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MMAKSALRENGTNSETFRQRFRRFHYQEVAGPREAFSQLWELCCRWLRPEVRTKEQIVEL 60 61 LVLEQFLTVLPGEIQNWVQEQCPENGEEAVTLVEDLEREPGRPRSSVTVSVKGQEVRLEK 120 121 MTPPKSSQELLSVRQESVEPQPRGVPKKERARSPDLGPQEQMNPKEKLKPFQRSGLPFPK 180 181 SGVVSRLEQGEPWIPDLLGSKEKELPSGSHIGDRRVHADLLPSKKDRRSWVEQDHWSFED 240 241 EKVAGVHWGYEETRTLLAILSQTEFYEALRNCHRNSQVYGAVAERLREYGFLRTLEQCRT 300 301 KFKGLQKSYRKVKSGHPPETCPFFEEMEALMSAQVIALPSNGLEAAASHSGLVGSDAETE 360 361 EPGQRGWQHEEGAEEAVAQESDSDDMDLEATPQDPNSAAPVVFRSPGGVHWGYEETKTYL 420 421 AILSETQFYEALRNCHRNSQLYGAVAERLWEYGFLRTPEQCRTKFKSLQTSYRKVKNGQA 480 481 PETCPFFEEMDALVSVRVAAPPNDGQEETASCPVQGTSEAEAQKQAEEADEATEEDSDDD 540 541 EEDTEIPPGAVITRAPVLFQSPRGFEAGFENEDNSKRDISEEVQLHRTLLARSERKIPRY 600 601 LHQGKGNESDCRSGRQWAKTSGEKRGKLTLPEKSLSEVLSQQRPCLGERPYKYLKYSKSF 660 661 GPNSLLMHQVSHQVENPYKCADCGKSFSRSARLIRHRRIHTGEKPYKCLDCGKSFRDSSN 720 721 FITHRRIHTGEKPYQCGECGKCFNQSSSLIIHQRTHTGEKPYQCEECGKSFNNSSHFSAH 780 781 RRIHTGERPHVCPDCGKSFSKSSDLRAHHRTHTGEKPYGCHDCGKCFSKSSALNKHGEIH 840 841 AREKLLTQSAPK |
| Interface Residues: | 636, 637, 640, 662, 663, 664, 678, 689, 690, 691, 692, 695, 699, 716, 717, 718, 719, 720, 722, 723, 724, 725, 726, 729, 744, 745, 746, 747, 748, 749, 751, 752, 772, 773, 774, 775, 776, 778, 779, 782, 800, 801, 802, 803, 804, 805, 806, 807, 811, 828, 829, 830, 831, 832, 835 |
| 3D-footprint Homologues: | 5v3j_F, 2kmk_A, 8ssq_A, 7w1m_H, 8ssu_A, 5kkq_D, 1f2i_J, 5ei9_F, 5yel_A, 7n5w_A, 6ml4_A, 6blw_A, 5k5i_A, 2gli_A, 1tf6_A, 4m9v_C, 8h9h_G, 2lt7_A, 2jpa_A, 1ubd_C, 3uk3_C, 1tf3_A, 6jnm_A, 1llm_D, 5kl3_A, 2wbs_A, 7txc_E, 7ysf_A, 6e94_A, 6a57_A, 8cuc_F, 1g2f_F, 6u9q_A, 2drp_D, 4x9j_A, 7y3m_I, 7y3l_A, 8gn3_A, 5yj3_D |
| Binding Motifs: | MA1602.1 yGTCTACrCrGs MA1602.2 yGTCTACrCrG |
| Publications: | Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Related annotations: | PaperBLAST |
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