Transcription Factor
| Accessions: | UP00056A (UniPROBE 20160601) |
| Names: | 4 (influences HLA class II expression), 4933412G19Rik, NYD-sp10, regulatory factor X, Rfx4 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q8HWA6 |
| Description: | regulatory factor X, 4 (influences HLA class II expression) |
| Length: | 113 |
| Pfam Domains: | 31-98 RFX DNA-binding domain 41-85 Poxvirus D5 protein-like |
| Sequence: (in bold interface residues) | 1 RYSSHTSLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLD 60 61 FCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYY |
| Interface Residues: | 73, 77, 90, 94, 99 |
| 3D-footprint Homologues: | 1dp7_P |
| Binding Motifs: | UP00056A_1 ymcCmTAGCAACsrw UP00056A_2 tmsCmTrGwTACssm |
| Binding Sites: | ATAGCAAC ATAGTTAC ATGGCAAC CGTAACTA CGTTACCA CGTTGCCA CGTTGCTA CTAGCAAC CTGGCAAC GGTAACCA GGTAACTA GGTTACCA GGTTGCCA GGTTGCTA GTAACCAA GTAGCAAC GTTACCAA GTTGCCAA GTTGCTAA TAGCAACA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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