Transcription Factor

						

			
Accessions: 5v3g_A (3D-footprint 20231221)

			
Names: D9IWL3_HUMAN, EC 2.1.1.43, Fragment, PR domain zinc finger protein 9
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: D9IWL3
Length: 168
Pfam Domains:      5-27 C2H2-type zinc finger
     5-27 Zinc finger, C2H2 type
     5-27 C2H2-type zinc finger
    19-42 Zinc-finger double domain
    33-55 C2H2-type zinc finger
    33-55 C2H2-type zinc finger
    33-55 Zinc finger, C2H2 type
    47-70 Zinc-finger double domain
    61-83 Zinc finger, C2H2 type
    61-83 C2H2-type zinc finger
    61-83 C2H2-type zinc finger
    75-99 Zinc-finger double domain
   89-111 Zinc finger, C2H2 type
   89-111 C2H2-type zinc finger
   89-111 C2H2-type zinc finger
  104-126 Zinc-finger double domain
  117-139 Zinc finger, C2H2 type
  117-139 C2H2-type zinc finger
  117-139 C2H2-type zinc finger
  131-156 Zinc-finger double domain
  145-167 Zinc finger, C2H2 type
  145-167 C2H2-type zinc finger
  145-167 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 SEKPYVCRECGRGFSNKSHLLRHQRTHTGEKPYVCRECGRGFRDKSHLLSHQRTHTGEKP   60
  61 YVCRECGRGFRDKSNLLSHQRTHTGEKPYVCRECGRGFSWQSVLLRHQRTHTGEKPYVCR  120
 121 ECGRGFRDKSNLLSHQRTHTGEKPYVCRECGRGFRNKSHLLRHQRTHT
Interface Residues: 16, 18, 19, 21, 22, 43, 44, 45, 46, 47, 50, 55, 61, 71, 72, 73, 74, 75, 76, 77, 78, 80, 81, 84, 99, 100, 101, 102, 103, 105, 106, 127, 128, 129, 130, 131, 133, 134, 135, 156, 157, 158, 159, 160, 162, 163
3D-footprint Homologues: 5und_A, 8ssu_A, 6wmi_A, 5k5l_F, 1tf6_A, 7w1m_H, 5v3j_F, 4x9j_A, 2i13_A, 1llm_D, 5kkq_D, 5ei9_F, 5kl3_A, 8ssq_A, 1f2i_J, 7ysf_A, 2lt7_A, 3uk3_C, 2gli_A, 6ml4_A, 5yel_A, 6e94_A, 6dta_B, 2kmk_A, 6jnm_A, 7n5w_A, 1tf3_A, 1g2f_F, 6blw_A, 2wbs_A, 6u9q_A, 5k5i_A, 7eyi_G, 8h9h_G, 6a57_A, 2jpa_A, 1ubd_C, 8ebt_K, 8ebx_K, 8cuc_F, 7y3l_A, 1mey_C, 2drp_D, 7txc_E, 7y3m_I, 8gn3_A, 4m9v_C, 5yj3_D
Binding Motifs: 5v3g_A GGGnAACGCTCACTGGGGTC
Binding Sites: 5v3g_B
5v3g_C
			
Publications: Patel A, Zhang X, Blumenthal RM, Cheng X. Structural basis of human PR/SET domain 9 (PRDM9) allele C-specific recognition of its cognate DNA sequence. J Biol Chem 292:15994-16002 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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