Transcription Factor
| Accessions: | Q96MR9 (JASPAR 2024) |
| Names: | ZN560_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q96MR9 |
| Length: | 790 |
| Pfam Domains: | 13-53 KRAB box 110-150 KRAB box 341-358 Zinc-finger double domain 347-368 C2H2-type zinc finger 348-370 Zinc finger, C2H2 type 348-370 C2H2-type zinc finger 362-386 Zinc-finger double domain 375-386 C2H2-type zinc finger 376-398 Zinc finger, C2H2 type 376-398 C2H2-type zinc finger 392-415 Zinc-finger double domain 404-426 C2H2-type zinc finger 419-441 Zinc-finger double domain 431-455 C2H2-type zinc finger 432-454 Zinc finger, C2H2 type 432-455 C2H2-type zinc finger 488-510 Zinc finger, C2H2 type 488-510 C2H2-type zinc finger 490-510 C2H2-type zinc finger 504-527 Zinc-finger double domain 516-538 Zinc finger, C2H2 type 516-538 C2H2-type zinc finger 531-554 Zinc-finger double domain 543-566 C2H2-type zinc finger 544-566 Zinc finger, C2H2 type 544-566 C2H2-type zinc finger 559-582 Zinc-finger double domain 571-595 C2H2-type zinc finger 572-594 C2H2-type zinc finger 572-594 Zinc finger, C2H2 type 587-610 Zinc-finger double domain 599-622 C2H2-type zinc finger 600-622 Zinc finger, C2H2 type 600-622 C2H2-type zinc finger 614-638 Zinc-finger double domain 632-650 Zinc finger, C2H2 type 642-666 Zinc-finger double domain 655-678 C2H2-type zinc finger 656-678 C2H2-type zinc finger 711-730 C2H2-type zinc finger 712-734 Zinc finger, C2H2 type 712-734 C2H2-type zinc finger 726-751 Zinc-finger double domain 739-763 C2H2-type zinc finger 740-762 Zinc finger, C2H2 type 740-762 C2H2-type zinc finger 757-778 Zinc-finger double domain 768-790 C2H2-type zinc finger 768-790 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MAYCLTNCYQYSVTFEDTAVDFTQEEWILLDPVQRNLYRDVMLENYENVAKVGFQLFKPS 60 61 VISWLEEEELRTLQQGVLQDWAIKHQTSVSALQQEFWKIQTSNGIQMDLVTFDSVAVEFT 120 121 QEEWTLLDPAQRNLYSDVMLENYKNLSSVGYQLFKPSLISWLEEEEELSTLPRVLQEWKM 180 181 CLKTKGPALWQDNFCLKTLNGIQLARNQNGEELYDCKQCEDVFCKHPCLKTNMSTQNRGN 240 241 TSECIQYAKDLLSLYNKTSTIRKVSVFSKHGKSFRLILNVQVQRKCTQDKSFEGTDYGKA 300 301 FIYQSYLEAHRKTQSGEKLNEWKQCGEAFTHSTSHAVNVETHIIKNPYECKECGKDFRYP 360 361 THLNNHMQTHIGIKPYKCKHCGKTFTVPSGFLEHVRTHTGEKPYGCKECGKAFGTSAGLI 420 421 EHIRCHAREKTFKCDHCGKAFISYPSLFGHLRVHNGEKPYEHKEYGKAFGTSSGVIEDRR 480 481 SNTGQKRFDCDQCGKVFVSFSSLFAHLRTHTGEKPFKCYKCGKPFTSSACLRIHMRTHTE 540 541 ERLYQCKKCGKAFTKCSYLTKHLRTHAGEKPYECMKCGKAFTERSYLTKHLRRHSGEKPY 600 601 ECKKCGKAFTERSDLTKHLRRHTGDKPYEYKDCGKAFVVSSSLVDHLRTHTGYKPYKCNA 660 661 CEKAYSRSCVLTQHLKTHAAEKTSECNACGNSFRNSMCFHDRLKTLTKIKPYKCKDCGKA 720 721 FTCHSDLTNHVRIHTGEKPYKCKECGKAFRTSSGRIQHLRTHMGEKPFECDQCGKAFASF 780 781 SARIAHLKTH |
| Interface Residues: | 358, 359, 361, 362, 365, 387, 388, 389, 390, 393, 394, 397, 415, 417, 418, 421, 443, 445, 446, 449, 467, 470, 471, 472, 473, 498, 499, 500, 501, 502, 505, 508, 526, 527, 529, 530, 532, 533, 537, 539, 544, 553, 554, 555, 556, 557, 558, 561, 565, 582, 583, 584, 585, 586, 588, 589, 591, 592, 593, 595, 610, 611, 612, 613, 614, 616, 617, 639, 640, 641, 642, 643, 645, 666, 667, 668, 669, 670, 673, 695, 696, 699, 722, 723, 725, 726, 729, 750, 751, 752, 753, 754, 756, 757, 758, 779, 780, 781, 782, 783, 785, 786 |
| 3D-footprint Homologues: | 7w1m_H, 8gn3_A, 5kl3_A, 8ssq_A, 5v3j_F, 8cuc_F, 7y3l_A, 5kkq_D, 5k5i_A, 7y3m_I, 2gli_A, 1tf6_A, 5yj3_D, 6e94_A, 7ysf_A, 2lt7_A, 5yel_A, 2kmk_A, 7n5w_A, 6u9q_A, 5ei9_F, 7txc_E, 6ml4_A, 2drp_D, 8h9h_G, 6a57_A, 1ubd_C, 3uk3_C, 8ssu_A, 2wbs_A, 2jpa_A, 6blw_A, 1tf3_A, 6jnm_A, 4x9j_A, 1f2i_J, 1g2f_F, 1llm_D, 5k5l_F, 4m9v_C |
| Binding Motifs: | UN0631.1 rCCACTGCACTCCAGCCTGGGyrA |
| Binding Sites: | UN0631.1.1 UN0631.1.10 UN0631.1.11 UN0631.1.12 UN0631.1.13 UN0631.1.14 UN0631.1.15 UN0631.1.16 / UN0631.1.17 UN0631.1.17 / UN0631.1.18 UN0631.1.18 / UN0631.1.19 UN0631.1.19 / UN0631.1.20 UN0631.1.2 UN0631.1.20 UN0631.1.3 UN0631.1.4 UN0631.1.5 UN0631.1.6 UN0631.1.7 UN0631.1.8 UN0631.1.9 UN0631.1.16 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.