Transcription Factor
| Accessions: | SRF_DBD (HumanTF 1.0) |
| Names: | Serum response factor, SRF, SRF_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | P11831 |
| Notes: | Ensembl ID: ENSG00000112658; DNA-binding domain sequence; TF family: MADS; Clone source: MGC |
| Length: | 119 |
| Pfam Domains: | 27-77 SRF-type transcription factor (DNA-binding and dimerisation domain) |
| Sequence: (in bold interface residues) | 1 GYGPVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQ 60 61 VLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDPTTDQRMSATGF |
| Interface Residues: | 18, 21, 22, 33, 36, 37, 41 |
| 3D-footprint Homologues: | 1hbx_A, 7xuz_H, 8q9r_F, 8q9n_B, 8q9p_B, 1c7u_A, 1n6j_A, 8q9q_A, 1egw_B, 1mnm_A |
| Binding Motifs: | SRF_DBD aCCATATAwGGy |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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