Transcription Factor

Accessions: 2ere_A (3D-footprint 20231221), 2ere_B (3D-footprint 20231221)
Names: LEUR_YEAST, Regulatory protein LEU3
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P08638
Length: 60
Pfam Domains: 2-36 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence:
(in bold interface residues)
1 FACVECRQQKSKCDAHPCTKCAKKNVPCILKRDFRRTYKRARNEAIEKRFKELTRTLTNL 60
Interface Residues: 9, 10, 11, 25, 36
3D-footprint Homologues: 2er8_C, 1pyi_A, 6o19_A, 1zme_D, 6gys_C
Binding Motifs: 2ere_B cCGG
2ere_AB CCGgnncCGG
Binding Sites: 2ere_C / 2ere_D
Publications: Fitzgerald M.X, Rojas J.R, Kim J.M, Kohlhaw G.B, Marmorstein R. Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein. Structure (London, England : 1993) 14:725-35 (2006). [Pubmed]
Related annotations: PaperBLAST

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