Transcription Factor
| Accessions: | 5hod_A (3D-footprint 20231221) |
| Names: | LHX4_HUMAN, LIM homeobox protein 4, LIM/homeobox protein Lhx4 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q969G2 |
| Length: | 61 |
| Pfam Domains: | 3-59 Homeobox domain 16-55 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 GAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRL 60 61 K |
| Interface Residues: | 3, 4, 5, 6, 44, 45, 47, 48, 51, 52, 55, 56, 59 |
| 3D-footprint Homologues: | 1puf_A, 2h1k_B, 1fjl_B, 6a8r_A, 3cmy_A, 1ig7_A, 5zfz_A, 8pop_A, 3lnq_A, 2lkx_A, 1zq3_P, 1jgg_B, 6m3d_C, 2ld5_A, 3a01_E, 6ryd_F, 1au7_A, 5hod_A, 1puf_B, 2hdd_A, 1b72_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 3d1n_M, 2hos_A, 4cyc_A, 2d5v_B, 5flv_I, 3l1p_A, 7q3o_C, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 5zjt_E, 4qtr_D, 4xrm_B, 1nk2_P, 6wig_A, 8g87_X, 6es3_K, 1o4x_A, 7psx_B, 1du0_A |
| Binding Motifs: | 5hod_A tnattaC 5hod_AD CAATnAGnnGTAATna |
| Binding Sites: | 5hod_B 5hod_C |
| Publications: | Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Related annotations: | PaperBLAST |
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