Transcription Factor
| Accessions: | Q9Y5W3 (JASPAR 2024) |
| Names: | KLF2_HUMAN, Krueppel-like factor 2, Lung krueppel-like factor |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9Y5W3 |
| Length: | 355 |
| Pfam Domains: | 272-296 C2H2-type zinc finger 272-296 Zinc finger, C2H2 type 288-310 Zinc-finger double domain 302-326 C2H2-type zinc finger 302-326 Zinc finger, C2H2 type 319-343 Zinc-finger double domain 332-354 Zinc finger, C2H2 type 332-354 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MALSEPILPSFSTFASPCRERGLQERWPRAEPESGGTDDDLNSVLDFILSMGLDGLGAEA 60 61 APEPPPPPPPPAFYYPEPGAPPPYSAPAGGLVSELLRPELDAPLGPALHGRFLLAPPGRL 120 121 VKAEPPEADGGGGYGCAPGLTRGPRGLKREGAPGPAASCMRGPGGRPPPPPDTPPLSPDG 180 181 PARLPAPGPRASFPPPFGGPGFGAPGPGLHYAPPAPPAFGLFDDAAAAAAALGLAPPAAR 240 241 GLLTPPASPLELLEAKPKRGRRSWPRKRTATHTCSYAGCGKTYTKSSHLKAHLRTHTGEK 300 301 PYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRHM |
| Interface Residues: | 281, 283, 284, 285, 286, 287, 288, 290, 291, 293, 294, 297, 313, 314, 315, 316, 317, 318, 320, 321, 322, 325, 342, 343, 344, 345, 346, 347, 348, 349, 350, 353 |
| 3D-footprint Homologues: | 5k5i_A, 6jnm_A, 8cuc_F, 6ml4_A, 7n5w_A, 3uk3_C, 1tf3_A, 5und_A, 2gli_A, 1g2f_F, 7eyi_G, 8ssu_A, 1tf6_A, 4x9j_A, 2i13_A, 1llm_D, 6blw_A, 5kkq_D, 1ubd_C, 6u9q_A, 5ei9_F, 1mey_C, 5kl3_A, 7ysf_A, 6wmi_A, 2kmk_A, 8ssq_A, 7w1m_H, 5v3j_F, 8h9h_G, 2lt7_A, 7y3m_I, 6e94_A, 6a57_A, 2jpa_A, 8gn3_A, 7y3l_A, 5k5l_F, 2wbs_A, 5yel_A, 7txc_E, 2drp_D, 1f2i_J, 5yj3_D, 4m9v_C |
| Binding Motifs: | MA1515.1 srCCmCrCCCw MA1515.2 CCmCrCCC |
| Publications: | Bieker JJ. Krüppel-like factors: three fingers in many pies. J Biol Chem 276:34355-8 (2001). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.