Transcription Factor

						

			
Accessions: 4wlw_A (3D-footprint 20231221)

			
Names: Copper efflux regulator, Copper export regulator, CUER_ECOLI, HTH-type transcriptional regulator CueR
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0A9G4
Length: 130
Pfam Domains:      1-67 MerR HTH family regulatory protein
     2-39 MerR family regulatory protein
   45-108 MerR, DNA binding
Sequence: 
(in bold interface residues)		   1 MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNL   60
  61 EESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMRDQLLALANACPGDDSADC  120
 121 PIIENLSGCC
Interface Residues: 15, 18, 19, 22, 23, 36, 37
3D-footprint Homologues: 6xl5_H, 4r24_B, 6jgx_B, 1r8e_A, 7ckq_G, 4r4e_B, 6ldi_G, 2vz4_A, 7tea_B, 5c8e_C, 6xh7_H, 2zhg_A, 7tec_A, 5d8c_A, 1r8d_B
Binding Motifs: 4wlw_A CcntCCAG
Binding Sites: 4wlw_X
4wlw_Y
			
Publications: Philips SJ, Canalizo-Hernandez M, Yildirim I, Schatz GC, Mondragón A, O'Halloran TV. TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter 349:877-81 (Science.). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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