Transcription Factor

Accessions: Q03014 (JASPAR 2024)
Names: Hematopoietically-expressed homeobox protein HHEX, HHEX_HUMAN, Homeobox protein HEX, Homeobox protein PRH
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q03014
Length: 270
Pfam Domains: 142-194 Homeobox domain
Sequence:
(in bold interface residues)
1 MQYPHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTS 60
61 LVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPL 120
121 GKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQ 180
181 VKTWFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSP 240
241 ASQEDLESEISEDSDQEVDIEGDKSYFNAG
Interface Residues: 135, 137, 138, 139, 140, 141, 142, 143, 144, 146, 148, 179, 180, 182, 183, 186, 187, 190, 191, 193, 194, 199, 201
3D-footprint Homologues: 6x1j_A, 2h1k_B, 1nk2_P, 1puf_A, 5flv_I, 2r5y_A, 7psx_B, 1b72_A, 5jlw_D, 3rkq_B, 2ld5_A, 6es3_K, 7q3o_C, 2lkx_A, 1mnm_C, 1k61_B, 1le8_B, 7xrc_C, 1e3o_C, 4j19_B, 1au7_A, 2xsd_C, 1le8_A, 1ig7_A, 1jgg_B, 6m3d_C, 3cmy_A, 2hdd_A, 5zjt_E, 1puf_B, 5hod_A, 3lnq_A, 1fjl_B, 6a8r_A, 4qtr_D, 1zq3_P, 1o4x_A, 4xrs_G, 3a01_E, 1du0_A, 5zfz_A, 4cyc_A, 2hos_A
Binding Motifs: UN0309.1 mwrAGCAAACAkw
Binding Sites: UN0309.1.1
UN0309.1.10
UN0309.1.11
UN0309.1.12
UN0309.1.13
UN0309.1.14
UN0309.1.15
UN0309.1.16
UN0309.1.17
UN0309.1.18
UN0309.1.19
UN0309.1.2
UN0309.1.20
UN0309.1.3
UN0309.1.4
UN0309.1.5
UN0309.1.6
UN0309.1.7
UN0309.1.8
UN0309.1.9
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.