Transcription Factor

Accessions: 5ef6_J (3D-footprint 20231221), 5no6_A (3D-footprint 20231221), 5no6_B (3D-footprint 20231221)
Names: Homeobox protein Hox-B13, HXB13_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q92826
Length: 62
Pfam Domains: 1-57 Homeobox domain
Sequence:
(in bold interface residues)
1 RKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLA 60
61 KV
Interface Residues: 1, 2, 3, 4, 12, 28, 30, 42, 43, 45, 46, 49, 50, 53, 54, 57
3D-footprint Homologues: 2h1k_B, 1puf_A, 3cmy_A, 6a8r_A, 1fjl_B, 5zfz_A, 1ig7_A, 2lkx_A, 1nk2_P, 1zq3_P, 7q3o_C, 6es3_K, 2ld5_A, 3a01_E, 5zjt_E, 4cyc_A, 1jgg_B, 2hdd_A, 7psx_B, 2r5y_A, 6m3d_C, 1au7_A, 5jlw_D, 3lnq_A, 2hos_A, 4xrs_G, 1b72_A, 3rkq_B, 5flv_I, 6vz3_A, 6vu3_A, 1e3o_C, 2xsd_C, 1le8_A, 1le8_B, 1du0_A, 6fqq_E, 5hod_A, 1mnm_C, 4qtr_D, 1puf_B, 1k61_B, 1o4x_A, 7xrc_C, 6fqp_B
Binding Motifs: 5ef6_J TtTa
5no6_AN GGAATgcnATAaA
5no6_BI GAATGynATAAm
Binding Sites: 5ef6_K
5ef6_L
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Related annotations: PaperBLAST

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