Transcription Factor

						

			
Accessions: T025935_1.02 (CISBP 1.02), FOSL2_MOUSE (HOCOMOCO 10)

			
Names: Fosl2, T025935_1.02;, Fos-related antigen 2, FOSL2_MOUSE, FRA-2
Organisms: Mus musculus
Libraries: CISBP 1.02 1, HOCOMOCO 10 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]

2 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Notes: experiment type:PBM, family:bZIP
Length: 326
Pfam Domains:   122-181 bZIP transcription factor
  124-176 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL   60
  61 QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS  120
 121 PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKL  180
 181 EFMLVAHGPVCKISPEERRSPPTSGLQSLRGTGSAVGPVVVKQEPPEEDSPSSSAGMDKT  240
 241 QRSVIKPISIAGGGFYGEEPLHTPIVVTSTPAITPGTSNLVFTYPNVLEQESPSSPSESC  300
 301 SKAHRRSSSSGDQSSDSLNSPTLLAL
Interface Residues: 130, 131, 134, 135, 137, 138, 141, 142, 145, 268, 269, 273
3D-footprint Homologues: 7x5e_E, 7x5e_F, 2wt7_A, 2wt7_B, 4eot_A, 1nwq_C, 6mg1_B, 1skn_P, 2dgc_A, 5vpe_C, 5vpe_D, 1kqq_A
Binding Motifs: M0301_1.02 GATGACky
FOSL2_MOUSE.H10MO.A|M01092 ggrTGAGTCAy
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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