Transcription Factor

Accessions: 6es3_K (3D-footprint 20231221)
Names: Caudal-type homeobox protein 2, CDX-3, CDX2_HUMAN, Homeobox protein CDX-2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 72
Pfam Domains: 5-60 Homeobox domain
Sequence:
(in bold interface residues)
1 RTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERK 60
61 INKKKLQQQQQQ
Interface Residues: 4, 5, 6, 7, 45, 46, 48, 49, 52, 53, 56, 57, 58, 59, 60
3D-footprint Homologues: 3d1n_M, 1puf_A, 3lnq_A, 1nk2_P, 1jgg_B, 7q3o_C, 6es3_K, 2ld5_A, 2h1k_B, 7psx_B, 2lkx_A, 6a8r_A, 3cmy_A, 2hdd_A, 1fjl_B, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 1ig7_A, 5zfz_A, 4cyc_A, 2d5v_B, 5flv_I, 5zjt_E, 3a01_E, 1e3o_C, 1au7_A, 1le8_A, 7xrc_C, 2xsd_C, 1mnm_C, 5hod_A, 1puf_B, 1k61_B, 4xrm_B, 1zq3_P, 1b72_A, 1o4x_A, 1le8_B, 1du0_A, 3l1p_A, 8g87_X, 4qtr_D, 6m3d_C
Binding Motifs: 6es3_K rTnGTAAw
Binding Sites: 6es3_A
6es3_F
Publications: Morgunova E, Yin Y, Das PK, Jolma A, Zhu F, Popov A, Xu Y, Nilsson L, Taipale J. Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife : (2018). [Pubmed]
Related annotations: PaperBLAST

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