Transcription Factor

Accessions: Q96C28 (JASPAR 2024)
Names: ZN707_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q96C28
Length: 371
Pfam Domains: 8-48 KRAB box
191-213 Zinc-finger double domain
204-226 Zinc finger, C2H2 type
204-226 C2H2-type zinc finger
204-226 C2H2-type zinc finger
218-242 Zinc-finger double domain
232-254 C2H2-type zinc finger
247-271 Zinc-finger double domain
260-282 Zinc finger, C2H2 type
260-278 C2H2-type zinc finger
260-282 C2H2-type zinc finger
274-299 Zinc-finger double domain
288-310 C2H2-type zinc finger
288-310 Zinc finger, C2H2 type
288-311 C2H2-type zinc finger
302-325 Zinc-finger double domain
315-326 C2H2-type zinc finger
316-338 Zinc finger, C2H2 type
331-355 Zinc-finger double domain
344-366 C2H2-type zinc finger
344-366 Zinc finger, C2H2 type
344-368 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MDMAQEPVTFRDVAIYFSREEWACLEPSQRALYRDVMLDNFSSVAALGFCSPRPDLVSRL 60
61 EQWEEPWVEDRERPEFQAVQRGPRPGARKSADPKRPCDHPAWAHKKTHVRRERAREGSSF 120
121 RKGFRLDTDDGQLPRAAPERTDAKPTAFPCQVLTQRCGRRPGRRERRKQRAVELSFICGT 180
181 CGKALSCHSRLLAHQTVHTGTKAFECPECGQTFRWASNLQRHQKNHTREKPFCCEACGQA 240
241 FSLKDRLAQHRKVHTEHRPYSCGDCGKAFKQKSNLLRHQLVHTGERPFYCADCGKAFRTK 300
301 ENLSHHQRVHSGEKPYTCAECGKSFRWPKGFSIHRRLHLTKRFYECGHCGKGFRHLGFFT 360
361 RHQRTHRHGEV
Interface Residues: 164, 168, 187, 189, 190, 193, 214, 215, 216, 217, 218, 220, 221, 232, 242, 243, 244, 245, 246, 248, 249, 251, 252, 253, 255, 270, 271, 272, 273, 274, 276, 277, 298, 299, 300, 301, 302, 303, 304, 305, 306, 327, 328, 329, 330, 331, 332, 333, 334, 354, 355, 357, 358
3D-footprint Homologues: 8ssu_A, 8ssq_A, 1tf6_A, 5v3j_F, 7w1m_H, 8cuc_F, 7y3l_A, 7n5w_A, 6u9q_A, 5yel_A, 5yj3_D, 5k5i_A, 1llm_D, 6ml4_A, 2drp_D, 5k5l_F, 8h9h_G, 2kmk_A, 5kkq_D, 2wbs_A, 5ei9_F, 6e94_A, 7ysf_A, 2lt7_A, 6a57_A, 2jpa_A, 1ubd_C, 1tf3_A, 6jnm_A, 4x9j_A, 2gli_A, 1f2i_J, 8gn3_A, 1g2f_F, 5kl3_A, 7txc_E, 6blw_A, 7y3m_I, 3uk3_C, 4m9v_C
Binding Motifs: MA1715.1 / UN0214.1 CCCCACTYCTGGTAC
Binding Sites: MA1715.1.1 / UN0214.1.1
MA1715.1.10 / UN0214.1.10
MA1715.1.11 / UN0214.1.11
MA1715.1.12 / UN0214.1.12
UN0214.1.13 / UN0214.1.14 / UN0214.1.15
MA1715.1.13 / UN0214.1.16
UN0214.1.17
MA1715.1.14 / UN0214.1.18
MA1715.1.15 / MA1715.1.6 / UN0214.1.19 / UN0214.1.7
UN0214.1.2
UN0214.1.20
MA1715.1.2 / UN0214.1.3
MA1715.1.3 / UN0214.1.4
MA1715.1.4 / UN0214.1.5
UN0214.1.6
MA1715.1.8 / UN0214.1.8
MA1715.1.9 / UN0214.1.9
MA1715.1.16
MA1715.1.17
MA1715.1.18
MA1715.1.19
MA1715.1.20
MA1715.1.5
MA1715.1.7
Publications: ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489:57-74 (2012). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.