Transcription Factor
| Accessions: | PTF1A_HUMAN (HOCOMOCO 10) |
| Names: | bHLH transcription factor p48, bHLHa29, Class A basic helix-loop-helix protein 29, p48 DNA-binding subunit of transcription factor PTF1, Pancreas transcription factor 1 subunit alpha, Pancreas-specific transcription factor 1a, PTF1-p48, PTF1A_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] |
| Uniprot: | Q7RTS3 |
| Length: | 328 |
| Pfam Domains: | 165-215 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MDAVLLEHFPGGLDAFPSSYFDEDDFFTDQSSRDPLEDGDELLADEQAEVEFLSHQLHEY 60 61 CYRDGACLLLQPAPPAAPLALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPS 120 121 CLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSIN 180 181 DAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGG 240 241 RLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKV 300 301 WTPEDPRKLNSKSSFNNIENEPPFEFVS |
| Interface Residues: | 165, 168, 169, 171, 172, 173, 175, 176, 201 |
| 3D-footprint Homologues: | 7z5k_B, 2ypa_A, 4h10_A, 6od3_F, 5eyo_A, 7rcu_E, 5i50_B, 6g1l_A, 2ql2_D, 8osl_P, 2ypa_B, 2ql2_A, 7ssa_L |
| Binding Motifs: | PTF1A_HUMAN.H10MO.C|M01470 crGGrAAmwsmaCAssTGysm |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.