Transcription Factor

Accessions: 3hdd_B (3D-footprint 20231221)
Names: ENGRAILED HOMEODOMAIN, HMEN_DROME
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P02836
Length: 56
Pfam Domains: 1-56 Homeobox domain
Sequence:
(in bold interface residues)
1 RPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKK
Interface Residues: 1, 2, 3, 41, 42, 44, 45, 48, 49, 52, 53, 56
3D-footprint Homologues: 3lnq_A, 1jgg_B, 6m3d_C, 2lkx_A, 1zq3_P, 5zjt_E, 1ig7_A, 4j19_B, 3a01_E, 2d5v_B, 5hod_A, 2ld5_A, 1puf_A, 6a8r_A, 3cmy_A, 2h1k_B, 5jlw_D, 3rkq_B, 6es3_K, 4xrs_G, 1au7_A, 3d1n_M, 2hdd_A, 7psx_B, 1nk2_P, 5zfz_A, 1fjl_B, 4cyc_A, 2r5y_A, 5flv_I, 1b72_A, 2hos_A, 7q3o_C, 1e3o_C, 1le8_A, 6fqq_E, 1le8_B, 1du0_A, 8g87_X, 4qtr_D, 1mnm_C, 1puf_B, 1k61_B, 6fqp_B, 3l1p_A, 1o4x_A
Binding Motifs: 3hdd_AB GTAATAACnTTA
Binding Sites: 3hdd_C
3hdd_D
Publications: Fraenkel E, Rould M.A, Chambers K.A, Pabo C.O. Engrailed homeodomain-DNA complex at 2.2 A resolution: a detailed view of the interface and comparison with other engrailed structures. Journal of molecular biology 284:351-61 (1998). [Pubmed]
Related annotations: PaperBLAST

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