Transcription Factor

						

			
Accessions: 5dui_A (3D-footprint 20231221)

			
Names: Forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, FOXO1_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q12778
Length: 86
Pfam Domains:      4-83 Fork head domain
Sequence: 
(in bold interface residues)		   1 WGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSL   60
  61 HSKFIRVQNEGTGKSSWWMLNPEGGK
Interface Residues: 20, 22, 27, 29, 46, 49, 51, 52, 53, 55, 56, 57, 59, 60, 69, 70, 74
3D-footprint Homologues: 1a73_A, 3l2c_A, 7vox_H, 2hdc_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 3qrf_G
Binding Motifs: 5dui_A tTtA
5dui_AB TtnnnnnnnnnnnTAAA
Binding Sites: 5dui_C
5dui_D
			
Publications: Singh P, Han EH, Endrizzi JA, O'Brien RM, Chi YI. Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter. J Struct Biol 198:54-64 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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