Transcription Factor

Accessions: 4uus_B (3D-footprint 20231221)
Names: Dpbx, EXD_DROME, Homeobox protein extradenticle, HOMEOTIC PROTEIN EXTRADENTICLE
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P40427
Length: 69
Pfam Domains: 1-55 Homeobox domain
14-52 Homeobox KN domain
Sequence:
(in bold interface residues)
1 NFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKA 60
61 QEEANLYAA
Interface Residues: 40, 41, 43, 44, 47, 48, 51, 52, 55
3D-footprint Homologues: 5jlw_D, 2ld5_A, 4j19_B, 7q3o_C, 1ic8_B, 1le8_A, 1ig7_A, 4xrm_B, 3d1n_M, 2hdd_A, 1le8_B, 6m3d_C, 1du0_A, 4cyc_A, 2r5y_A, 1zq3_P, 1jgg_B, 6es3_K, 4xrs_G, 3l1p_A, 1mnm_C, 7psx_B, 1fjl_B, 5zfz_A, 3a01_E, 2d5v_B, 1k61_B, 6fqp_B, 5flv_I, 3lnq_A, 1puf_A, 5zjt_E, 4qtr_D, 3cmy_A, 2h1k_B, 6fqq_E, 1b72_A, 5hod_A, 3rkq_B, 2lkx_A, 1puf_B, 8g87_X, 6a8r_A, 2hos_A
Binding Motifs: 4uus_AB cnATATATCA
Binding Sites: 4uus_C
4uus_D
Publications: Foos N, Maurel-Zaffran C, Maté M.J, Vincentelli R, Hainaut M, Berenger H, Pradel J, Saurin A.J, Ortiz-Lombardía M, Graba Y. A flexible extension of the Drosophila ultrabithorax homeodomain defines a novel Hox/PBC interaction mode. Structure (London, England : 1993) 23:270-9 (2015). [Pubmed]
Related annotations: PaperBLAST

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