Transcription Factor

						

			
Accessions: Q9C0K0 (JASPAR 2024)

			
Names: B-cell CLL/lymphoma 11B, B-cell lymphoma/leukemia 11B, BC11B_HUMAN, BCL-11B, COUP-TF-interacting protein 2, hRit1, Radiation-induced tumor suppressor gene 1 protein
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9C0K0
Length: 894
Pfam Domains:     56-82 C2H2-type zinc finger
  428-449 Zinc finger, C2H2 type
  429-449 C2H2-type zinc finger
  429-449 C2H2-type zinc finger
  441-464 Zinc-finger double domain
  455-477 C2H2-type zinc finger
  455-477 Zinc finger, C2H2 type
  797-818 C2H2-type zinc finger
  797-818 Zinc finger, C2H2 type
  798-818 C2H2-type zinc finger
  810-834 Zinc-finger double domain
  824-846 Zinc finger, C2H2 type
  824-846 C2H2-type zinc finger
  853-875 C2H2-type zinc finger
  854-877 C2H2-type zinc finger
  854-877 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MSRRKQGNPQHLSQRELITPEADHVEAAILEEDEGLEIEEPSGLGLMVGGPDPDLLTCGQ   60
  61 CQMNFPLGDILVFIEHKRKQCGGSLGACYDKALDKDSPPPSSRSELRKVSEPVEIGIQVT  120
 121 PDEDDHLLSPTKGICPKQENIAGPCRPAQLPAVAPIAASSHPHSSVITSPLRALGALPPC  180
 181 LPLPCCSARPVSGDGTQGEGQTEAPFGCQCQLSGKDEPSSYICTTCKQPFNSAWFLLQHA  240
 241 QNTHGFRIYLEPGPASSSLTPRLTIPPPLGPEAVAQSPLMNFLGDSNPFNLLRMTGPILR  300
 301 DHPGFGEGRLPGTPPLFSPPPRHHLDPHRLSAEEMGLVAQHPSAFDRVMRLNPMAIDSPA  360
 361 MDFSRRLRELAGNSSTPPPVSPGRGNPMHRLLNPFQPSPKSPFLSTPPLPPMPPGGTPPP  420
 421 QPPAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHK  480
 481 AGSLAGRSDDGLSAASSPEPGTSELAGEGLKAADGDFRHHESDPSLGHEPEEEDEEEEEE  540
 541 EEELLLENESRPESSFSMDSELSRNRENGGGGVPGVPGAGGGAAKALADEKALVLGKVME  600
 601 NVGLGALPQYGELLADKQKRGAFLKRAAGGGDAGDDDDAGGCGDAGAGGAVNGRGGGFAP  660
 661 GTEPFPGLFPRKPAPLPSPGLNSAAKRIKVEKDLELPPAALIPSENVYSQWLVGYAASRH  720
 721 FMKDPFLGFTDARQSPFATSSEHSSENGSLRFSTPPGDLLDGGLSGRSGTASGGSTPHLG  780
 781 GPGPGRPSSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLT  840
 841 RHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKWHGEHLLTNDVKIEQAERS
Interface Residues: 437, 438, 439, 440, 441, 444, 445, 466, 467, 468, 469, 470, 472, 473, 806, 807, 808, 809, 810, 812, 813, 815, 816, 819, 834, 835, 836, 837, 838, 840, 841, 845, 864, 865, 866, 867, 868, 869, 870, 871, 875
3D-footprint Homologues: 8cuc_F, 7y3l_A, 5kl3_A, 8gn3_A, 4m9v_C, 6jnm_A, 3uk3_C, 5v3j_F, 1tf3_A, 7n5w_A, 1g2f_F, 1ubd_C, 2kmk_A, 1llm_D, 7ysf_A, 8ssq_A, 7w1m_H, 6blw_A, 5k5l_F, 6u9q_A, 4x9j_A, 2gli_A, 8ssu_A, 1f2i_J, 5kkq_D, 5ei9_F, 8h9h_G, 7y3m_I, 2lt7_A, 6e94_A, 6a57_A, 2jpa_A, 7txc_E, 5k5i_A, 6ml4_A, 2drp_D, 5yel_A, 2wbs_A, 1tf6_A, 5yj3_D
Binding Motifs: UN0114.1 GTGAACGcwrwwgCTACAC
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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