Transcription Factor

Accessions: TFCP2L1 (HT-SELEX2 May2017)
Names: ENSG00000115112, TFCP2L1
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: CP2 experiment: HT-SELEX Hamming distance: 2 cycle: 4, TF family: CP2 experiment: Methyl-HT-SELEX Hamming distance: 2 cycle: 4
Length: 257
Pfam Domains: 35-240 CP2 transcription factor
Sequence:
(in bold interface residues)
1 FWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVKLH 60
61 EETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGWRW 120
121 SRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRKHG 180
181 GEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQEK 240
241 EKYQPSYETTILTECSP
Interface Residues: 218, 223, 226
3D-footprint Homologues: 5mpf_B
Binding Motifs: TFCP2L1_2 aCyrGttyraaCyrGt
TFCP2L1_methyl_1 aCyrGwtyraaCyrGw
Related annotations: PaperBLAST

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