Transcription Factor
| Accessions: | T015158_1.02 (CISBP 1.02), P41136 (JASPAR 2024) |
| Names: | Id2, T015158_1.02;, DNA-binding protein inhibitor ID-2, ID2_MOUSE, Inhibitor of differentiation 2, Inhibitor of DNA binding 2 |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:bHLH |
| Length: | 134 |
| Pfam Domains: | 37-76 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVT 60 61 KMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEF 120 121 PSELMSNDSKVLCG |
| Interface Residues: | 26, 36, 58 |
| 3D-footprint Homologues: | 4iqj_A, 2ql2_D, 6qzk_A |
| Binding Motifs: | M0189_1.02 rCACGTGr MA0617.1 rCACGTGr |
| Publications: | Langlands K., Yin X., Anand G., Prochownik E. V. Differential interactions of Id proteins with basic-helix-loop-helix transcription factors.. J. Biol. Chem. 272:19785-19793 (1997). [Pubmed] |
| Related annotations: | PaperBLAST |
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