Transcription Factor

Accessions: UP00216A (UniPROBE 20160601), Q9D350 (JASPAR 2024)
Names: 7420700M11Rik, AU015708, AU024152, Obox1, oocyte specific homeobox 1, Oocyte-specific homeobox 1, Q9D350_MOUSE
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9D350
Description: oocyte specific homeobox 1
Length: 204
Pfam Domains: 95-151 Homeobox domain
Sequence:
(in bold interface residues)
1 MAEGPSLHPKLQVDSNIPIEISSQIPQEPARNLAFQMRQSPLVTPGSTTKSSLSVPERNL 60
61 LKQESQGPSRQSGCMLLSDKYVNKQTGPMASRKFRKERTVYTKEQQGLLQKHFDECQYPN 120
121 KKKIVELALSVGVTKREIKIWFKNNRAKYRRMNLQNIEQVLPESNGSSKAVSESTHFPVV 180
181 ASDNGESMCSGTFGEDSIPKFNCS
Interface Residues: 49, 51, 53, 55, 62, 64, 90, 92, 93, 94, 95, 96, 97, 98, 100, 102, 104, 106, 136, 137, 139, 140, 143, 144, 147, 148, 151
3D-footprint Homologues: 6x1j_A, 1mnm_C, 5zfz_A, 2h1k_B, 1puf_A, 1fjl_B, 3cmy_A, 1ig7_A, 6a8r_A, 3d1n_M, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 2ld5_A, 7q3o_C, 6es3_K, 4xrs_G, 4j19_B, 3a01_E, 6m3d_C, 1au7_A, 5flv_I, 5zjt_E, 2hdd_A, 1b72_A, 5hod_A, 3rkq_B, 2r5y_A, 1puf_B, 2hos_A, 7psx_B, 5jlw_D, 4cyc_A, 1jgg_B, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 3l1p_A, 1o4x_A, 4qtr_D, 8g87_X, 4xrm_B, 1du0_A
Binding Motifs: UP00216A_1 ttarGGGGATTAAcwwy
PH0121.1 ttarGGGGATTAAcwwy
Binding Sites: AATAATCC
AGGATTAA
AGGATTAT
AGGGATTA
ATAATCCC
ATTAATCC
CGGATTAA
CGGGATTA
CTAATCCC
CTTAATCC
GAGGATTA
GATAATCC
GCTAATCC
GGATTAAA
GGATTAAC
GGATTATA
GGGATTAA
GGGATTAC
TAATCCCA
TAATCCTA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.