Transcription Factor
| Accessions: | UP00018A (UniPROBE 20160601) |
| Names: | AI385587, interferon regulatory factor 4, IRF-4, Irf4, LSIRF, Lymphocyte-specific interferon regulatory factor, NF-EM5, PU.1 interaction partner, Spip, Transcriptional activator PIP |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q64287 |
| Description: | interferon regulatory factor 4 |
| Length: | 144 |
| Pfam Domains: | 22-128 Interferon regulatory factor transcription factor |
| Sequence: (in bold interface residues) | 1 NLETGSRGSEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSVFRIPWKHAGKQD 60 61 YNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDP 120 121 YKVYRIVPEGAKKGAKQLTLDDTQ |
| Interface Residues: | 55, 57, 90, 94, 95, 97, 98, 101, 102 |
| 3D-footprint Homologues: | 1if1_B, 2o61_A, 2pi0_B, 2irf_L, 7oot_B |
| Binding Motifs: | UP00018A_1 mrwayCGAAACyrma UP00018A_2 rsyayTCTCGgwyks |
| Binding Sites: | AACGAAAC AAGTTTCG ACCGAAAC ACGAAACC AGTTTCGA AGTTTCGC AGTTTCGG ATCGAAAC CAGTTTCG CCGAAACC CGAAACCA CGAAACCC CGAAACCG CGAAACTA CGAAACTC GGTTTCGA GTTTCGAA GTTTCGGA TAGTTTCA TTTCGAAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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