Transcription Factor
| Accessions: | T098522_1.02 (CISBP 1.02), Q8IRC7 (JASPAR 2024) |
| Names: | Awh, T098522_1.02;, AWH_DROME, LIM/homeobox protein Awh, Protein arrowhead |
| Organisms: | Drosophila melanogaster |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8IRC7 |
| Notes: | experiment type:PBM, family:Homeodomain |
| Length: | 275 |
| Pfam Domains: | 8-65 LIM domain 69-125 LIM domain 149-205 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MKTELRSCAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKAD 60 61 YSKNFGAKCSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCK 120 121 AHYLETVEGGTTSSDEGCDGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLER 180 181 IASVTGLSKRVTQVWFQNSRARQKKHIHAGKNKIREPEGSSFARHINLQLTYSFQNNAQN 240 241 PMHLNGSKAGLYPTHESSMDELSQDSSVHCMPSEV |
| Interface Residues: | 78, 80, 87, 90, 106, 108, 109, 149, 150, 151, 152, 190, 191, 193, 194, 197, 198, 201, 202, 205 |
| 3D-footprint Homologues: | 1llm_D, 1fjl_B, 6a8r_A, 1ig7_A, 1nk2_P, 3cmy_A, 2h1k_B, 5zfz_A, 1puf_A, 3d1n_M, 1zq3_P, 3lnq_A, 1jgg_B, 2lkx_A, 6m3d_C, 7q3o_C, 2ld5_A, 6es3_K, 1puf_B, 7psx_B, 5hod_A, 3l1p_A, 2hos_A, 1b72_A, 3a01_E, 5jlw_D, 4xrs_G, 3rkq_B, 5flv_I, 2hdd_A, 1au7_A, 5zjt_E, 4cyc_A, 2r5y_A, 1e3o_C, 1le8_A, 4qtr_D, 1du0_A |
| Binding Motifs: | MA0167.1 yTAATTA M1097_1.02 ryTAATTAry |
| Binding Sites: | MA0167.1.1 MA0167.1.10 MA0167.1.11 MA0167.1.12 MA0167.1.13 MA0167.1.14 MA0167.1.15 MA0167.1.16 MA0167.1.17 MA0167.1.18 MA0167.1.19 MA0167.1.2 MA0167.1.20 MA0167.1.3 MA0167.1.4 MA0167.1.5 MA0167.1.6 MA0167.1.7 MA0167.1.8 MA0167.1.9 |
| Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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