Transcription Factor
| Accessions: | zen (DrosophilaTF 1.1), P09089 (JASPAR 2024) |
| Names: | Protein zerknuellt 1, ZEN-1, ZEN1_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 353 |
| Pfam Domains: | 91-147 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSSVMHYYPVHQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDH 60 61 CSPQHVHQQHVSSDENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRR 120 121 IEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSAHRGIVKRLMS 180 181 YSQDPREGTAAAEKRPMMAVAPVNPKPDYQASQKMKTEASTNNGMCSSADLSEILEHLAQ 240 241 TTAAPQVSTATSSTGTSTNSASSSSSGHYSYNVDLVLQSIKQDLEAAAQAWSKSKSAPIL 300 301 ATQSWHPSSQSQVPTSVHAAPSMNLSWGEPAAKSRKLSVNHMNPCVTSYNYPN |
| Interface Residues: | 91, 92, 93, 94, 132, 133, 135, 136, 139, 140, 143, 144, 147 |
| 3D-footprint Homologues: | 1fjl_B, 6a8r_A, 3cmy_A, 2h1k_B, 1ig7_A, 1puf_A, 3d1n_M, 5zfz_A, 1zq3_P, 3lnq_A, 1nk2_P, 2lkx_A, 1jgg_B, 6m3d_C, 2ld5_A, 7q3o_C, 6es3_K, 2hos_A, 5zjt_E, 4j19_B, 3a01_E, 7psx_B, 5hod_A, 1b72_A, 5jlw_D, 3rkq_B, 4xrs_G, 2hdd_A, 4cyc_A, 2r5y_A, 1puf_B, 5flv_I, 1le8_A, 1e3o_C, 4qtr_D, 1du0_A, 8g87_X, 3l1p_A |
| Binding Motifs: | MA0256.1 yTAATKA zen TCAwTTAAmT |
| Binding Sites: | MA0256.1.1 MA0256.1.13 MA0256.1.17 MA0256.1.11 MA0256.1.16 MA0256.1.18 MA0256.1.14 / MA0256.1.7 MA0256.1.10 MA0256.1.15 MA0256.1.3 MA0256.1.12 / MA0256.1.9 MA0256.1.19 MA0256.1.2 MA0256.1.4 MA0256.1.5 MA0256.1.6 MA0256.1.8 |
| Publications: | Hoey T., Levine M. Divergent homeo box proteins recognize similar DNA sequences in Drosophila. Nature 332:858-861 (1988). [Pubmed] Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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