Transcription Factor
| Accessions: | 1cqt_A (3D-footprint 20231221) |
| Names: | NF-A1, Oct-1, Octamer-binding protein 1, Octamer-binding transcription factor 1, OTF-1, PO2F1_HUMAN, POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 1 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P14859 |
| Length: | 134 |
| Pfam Domains: | 3-74 Pou domain - N-terminal to homeobox domain 75-131 Homeobox domain |
| Sequence: (in bold interface residues) | 1 EPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMC 60 61 KLKPLLEKWLNDAERKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRV 120 121 WFCNRRQKEKRINP |
| Interface Residues: | 26, 42, 43, 44, 45, 47, 48, 54, 58, 66, 75, 76, 77, 78, 82, 83, 86, 87, 116, 117, 119, 120, 123, 124, 127, 128, 131 |
| 3D-footprint Homologues: | 3d1n_M, 3l1p_A, 7u0g_M, 7xrc_C, 2xsd_C, 1o4x_A, 8g87_X, 1e3o_C, 1au7_A, 1lq1_D, 5zfz_A, 2r5y_A, 1ig7_A, 6a8r_A, 2h1k_B, 1puf_A, 1fjl_B, 3cmy_A, 1zq3_P, 6m3d_C, 1nk2_P, 2lkx_A, 7q3o_C, 6es3_K, 1b72_A, 2hos_A, 5zjt_E, 5hod_A, 3a01_E, 4xrs_G, 2hdd_A, 2ld5_A, 5jlw_D, 1le8_A, 3rkq_B, 5flv_I, 1du0_A, 4cyc_A, 2d5v_B, 1jgg_B, 7psx_B, 4qtr_D, 3lnq_A |
| Binding Motifs: | 1cqt_AI tATnCAAATA |
| Binding Sites: | 1cqt_M 1cqt_N |
| Publications: | Chasman D, Cepek K, Sharp P.A, Pabo C.O. Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface. Genes & development 13:2650-7 (1999). [Pubmed] |
| Related annotations: | PaperBLAST |
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