Transcription Factor

						

			
Accessions: YY1 (SMILE-seq 1.0)

			
Names: Delta transcription factor, INO80 complex subunit S, NF-E1, Transcriptional repressor protein YY1, TYY1_HUMAN, Yin and yang 1, YY-1, YY1
Organisms: Homo sapiens
Libraries: SMILE-seq 1.0 1
1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Uniprot: P25490
Notes: TF family: znfC2H2
Length: 413
Pfam Domains:   297-320 C2H2-type zinc finger
  325-347 Zinc finger, C2H2 type
  325-347 C2H2-type zinc finger
  340-365 Zinc-finger double domain
  353-377 C2H2-type zinc finger
  353-377 Zinc finger, C2H2 type
  369-395 Zinc-finger double domain
  383-407 C2H2-type zinc finger
  383-407 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MASGDTLYIATDGSEMPAEIVELHEIEVETIPVETIETTVVGEEEEEDDDDEDGGGGDHG   60
  61 GGGGHGHAGHHHHHHHHHHHPPMIALQPLVTDDPTQVHHHQEVILVQTREEVVGGDDSDG  120
 121 LRAEDGFEDQILIPVPAPAGGDDDYIEQTLVTVAAAGKSGGGGSSSSGGGRVKKGGGKKS  180
 181 GKKSYLSGGAGAAGGGGADPGNKKWEQKQVQIKTLEGEFSVTMWSSDEKKDIDHETVVEE  240
 241 QIIGENSPPDYSEYMTGKKLPPGGIPGIDLSDPKQLAEFARMKPRKIKEDDAPRTIACPH  300
 301 KGCTKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGC  360
 361 GKRFSLDFNLRTHVRIHTGDRPYVCPFDGCNKKFAQSTNLKSHILTHAKAKNN
Interface Residues: 308, 309, 310, 311, 312, 314, 315, 316, 317, 318, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 347, 361, 364, 365, 366, 367, 368, 369, 371, 372, 376, 393, 395, 396, 397, 398, 399, 400, 401, 402
3D-footprint Homologues: 7w1m_H, 8gn3_A, 5ei9_F, 6ml4_A, 4m9v_C, 7ysf_A, 6e94_A, 2jpa_A, 1ubd_C, 8ssq_A, 8ssu_A, 5kkq_D, 1tf3_A, 7n5w_A, 6jnm_A, 8cuc_F, 7y3l_A, 4x9j_A, 5kl3_A, 1tf6_A, 7txc_E, 2kmk_A, 6blw_A, 2gli_A, 8h9h_G, 7y3m_I, 2lt7_A, 6a57_A, 4gnx_Z, 5k5i_A, 3uk3_C, 5yj3_D, 1f2i_J, 1g2f_F, 5v3j_F, 1llm_D, 6u9q_A, 5yel_A, 2wbs_A
Binding Motifs: YY1 hawaATGGCggcc
			
Publications: Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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