Transcription Factor

						

			
Accessions: 1fos_F (3D-footprint 20231221)

			
Names: Activator protein 1, AP1, C-JUN PROTO-ONCOGENE PROTEIN, JUN_HUMAN, p39, Proto-oncogene c-Jun, Transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 57
Pfam Domains:      1-57 bZIP transcription factor
     1-54 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 RKRMRNRIAASKSRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVM
Interface Residues: 2, 3, 5, 6, 7, 9, 10, 13, 14
3D-footprint Homologues: 1gd2_G, 7x5e_F, 1nwq_C, 5vpe_D, 2dgc_A, 1dh3_C, 5t01_B
Binding Motifs: 1fos_EF TgACTca
Binding Sites: 1fos_A
1fos_B
			
Publications: Glover J. N. M., Harrison S. C. Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA. Nature 373:257-261 (1995). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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