Transcription Factor

Accessions: T044411_1.02 (CISBP 1.02)
Names: T044411_1.02;, ZIC1
Organisms: Homo sapiens
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: family:C2H2 ZF
Length: 136
Pfam Domains: 21-45 C2H2-type zinc finger
21-45 Zinc finger, C2H2 type
39-62 Zinc-finger double domain
51-73 C2H2-type zinc finger
51-73 Zinc finger, C2H2 type
52-71 Zinc-finger of C2H2 type
Sequence:
(in bold interface residues)
1 XPFGADSRLQSQAPDSGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSY 60
61 THPSSLRKHMKVHESSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHH 120
121 TAGHSALSSNFNEWYV
Interface Residues: 4, 5, 7, 8, 10, 11, 16, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 44, 61, 62, 63, 64, 65, 66, 67, 68, 69, 72, 92, 93, 94, 95, 96, 97
3D-footprint Homologues: 5v3j_F, 1tf3_A, 1ubd_C, 1mey_C, 5ei9_F, 2jpa_A, 7w1m_H, 7y3l_A, 3uk3_C, 7ysf_A, 2kmk_A, 8cuc_F, 1g2f_F, 7eyi_G, 6a57_A, 5k5l_F, 2lt7_A, 6ml4_A, 4x9j_A, 2i13_A, 1llm_D, 7n5w_A, 6blw_A, 5kkq_D, 2wbs_A, 6u9q_A, 8h9h_G, 7txc_E, 5kl3_A, 1f2i_J, 6wmi_A, 5k5i_A, 6jnm_A, 5und_A, 4m9v_C, 2gli_A, 7y3m_I, 5yel_A, 6e94_A, 8ssq_A, 8gn3_A, 1tf6_A, 2drp_D, 5yj3_D
Binding Motifs: M4147_1.02 kgGgtgGtc
Related annotations: PaperBLAST

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