Transcription Factor

Accessions: T018211_1.02 (CISBP 1.02)
Names: mdl-1, T018211_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:ChIP-seq, family:bHLH
Length: 281
Pfam Domains: 97-148 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MEQQLNLGHLLTAARLLDIGALDISSLDLGALTSTSSSPGSSSPAMFDLSNESELRSLFC 60
61 GKLKVDKKQSSCASNASTSSQPYCSSPPARKSSKHSRTAHNELEKTRRANLRGCLETLKM 120
121 LVPCVSDATRNTTLALLTRARDHIIELQDSNAAQMKKLNDLRDEQDELVAELAQLQADEE 180
181 VAQATSQACQTLSQSRPESRASSFTSTSSRDSPCYLEYSPSSKPMDSHKPTIIDLYAEGL 240
241 IPRGPITFPRPLVYPHNVFDLMNLPPTPFDVSQFLPINLQV
Interface Residues: 99, 100, 101, 103, 104, 107, 108, 127, 130, 135, 139
3D-footprint Homologues: 1an4_A, 7xi3_A, 5i50_B, 5nj8_D, 7f2f_B, 4h10_A, 5v0l_A, 1am9_A, 7ssa_L, 5eyo_A, 6g1l_A, 2ql2_D, 8osl_P, 6ny1_Y
Binding Motifs: M4709_1.02 gtCACGTG
Related annotations: PaperBLAST

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