Transcription Factor
| Accessions: | 6a8r_A (3D-footprint 20231221) |
| Names: | Double homeobox protein 10, Double homeobox protein 4, DUX4_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q9UBX2 |
| Length: | 58 |
| Pfam Domains: | 1-55 Homeobox domain 24-54 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 RRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHPGQ |
| Interface Residues: | 1, 2, 3, 4, 13, 14, 17, 42, 43, 45, 46, 49, 50, 53, 54, 57 |
| 3D-footprint Homologues: | 3cmy_A, 2h1k_B, 1ig7_A, 1puf_A, 5zfz_A, 3d1n_M, 1fjl_B, 6a8r_A, 3lnq_A, 1nk2_P, 2lkx_A, 1jgg_B, 1zq3_P, 2ld5_A, 7q3o_C, 5jlw_D, 6es3_K, 4xrs_G, 3rkq_B, 2hdd_A, 1au7_A, 5flv_I, 4cyc_A, 2r5y_A, 1puf_B, 5zjt_E, 3l1p_A, 2hos_A, 7psx_B, 1b72_A, 5hod_A, 3a01_E, 4f43_A, 4e0g_A, 1e3o_C, 4j19_B, 1le8_A, 1ic8_B, 1du0_A, 8g87_X, 4qtr_D, 4xrm_B, 6m3d_C |
| Binding Motifs: | 6a8r_A rTCA |
| Binding Sites: | 6a8r_E 6a8r_F |
| Publications: | Dong X, Zhang H, Cheng N, Li K, Meng G. DUX4(HD2)-DNA(ERG) structure reveals new insight into DUX4-Responsive-Element. Leukemia : (2018). [Pubmed] |
| Related annotations: | PaperBLAST |
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