Transcription Factor
Accessions: | T057701_1.02 (CISBP 1.02), Q9VDZ3 (JASPAR 2024) |
Names: | sqz, T057701_1.02;, SQZ_DROME |
Organisms: | Drosophila melanogaster |
Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | experiment type:B1H, family:C2H2 ZF |
Length: | 535 |
Pfam Domains: | 158-176 C2H2-type zinc finger 158-180 Zinc finger, C2H2 type 173-197 Zinc-finger double domain 186-208 C2H2-type zinc finger 186-208 Zinc finger, C2H2 type 200-226 Zinc-finger double domain 275-297 C2H2-type zinc finger 275-297 Zinc finger, C2H2 type |
Sequence: (in bold interface residues) | 1 MAELPTAPNGVPSGDYLHRSIDQLRSLGHLTTAQLVHDYKPFNISEFRQNVAERLDYSLK 60 61 NGLVQHQQQMVMEQQPHPDQQQQQHLHHPQQQQHPPQLKVSYSAPNSPPTPHEQQEQKYD 120 121 PNRSPPRQQMSSASGSGSNGSSPEEESRRGDGDQAKPYKCGSCSKSFANSSYLSQHTRIH 180 181 LGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRCHQT 240 241 DKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKHLQKHAEK 300 301 AEKQQHRHTAQVAAHQQHVPASGIGLNLQRQAMNDVNAAYWAKMGADSAAASLAEAIQQQ 360 361 LPQAGGQPYGNFASLQQQHQQQQQELLHHQRLADTPGHSHSPHEEAAGEDLVLRQSTPQH 420 421 HLQQQQQQQQQQQAQQQQQAQHQPSPGPGNSAFTPLSATVAPPPHLQQHRGPPGSAAAYL 480 481 YQQNAAAAAAAFPTQLISLHQIRNYAHQPGAAGLIAGDHLALGLSAVNAAKEKAQ |
Interface Residues: | 147, 148, 151, 158, 168, 169, 170, 171, 172, 174, 175, 176, 179, 196, 197, 198, 199, 200, 201, 202, 203, 204, 207, 226, 227, 228, 229, 230, 231, 232, 233, 237, 254, 255, 256, 257, 258, 260, 261, 265, 268, 269, 270, 271, 274, 286, 287, 288, 289, 292, 315, 316, 322, 323, 326, 329 |
3D-footprint Homologues: | 2jpa_A, 2kmk_A, 6jnm_A, 3uk3_C, 8cuc_F, 1tf3_A, 7y3l_A, 5v3j_F, 7n5w_A, 4x9j_A, 5kl3_A, 7ysf_A, 6wmi_A, 5ei9_F, 8ssq_A, 1mey_C, 7w1m_H, 5und_A, 1f2i_J, 5k5i_A, 8ssu_A, 2gli_A, 8gn3_A, 1g2f_F, 5kkq_D, 6u9q_A, 8h9h_G, 7eyi_G, 4m9v_C, 2i13_A, 6e94_A, 2lt7_A, 7y3m_I, 6a57_A, 1ubd_C, 5yel_A, 1llm_D, 7txc_E, 5yj3_D, 2drp_D, 6ml4_A, 6blw_A, 1tf6_A, 2wbs_A |
Binding Motifs: | M5211_1.02 rvtwhAyaAAAAAAAm UN0438.1 aaAAAAAAaa MA2108.1 AAAAAA |
Binding Sites: | UN0438.1.12 UN0438.1.1 UN0438.1.10 UN0438.1.11 UN0438.1.13 UN0438.1.14 UN0438.1.15 UN0438.1.16 UN0438.1.17 UN0438.1.18 UN0438.1.19 UN0438.1.2 UN0438.1.20 UN0438.1.3 UN0438.1.4 / UN0438.1.5 UN0438.1.6 UN0438.1.7 UN0438.1.8 UN0438.1.9 MA2108.1.1 / MA2108.1.10 / MA2108.1.11 / MA2108.1.12 / MA2108.1.13 / MA2108.1.14 / MA2108.1.15 / MA2108.1.16 / MA2108.1.17 / MA2108.1.18 / MA2108.1.19 / MA2108.1.2 / MA2108.1.20 / MA2108.1.3 / MA2108.1.4 / MA2108.1.5 / MA2108.1.6 / MA2108.1.7 / MA2108.1.8 / MA2108.1.9 |
Publications: | Zhu LJ, Christensen RG, Kazemian M, Hull CJ, Enuameh MS, Basciotta MD, Brasefield JA, Zhu C, Asriyan Y, Lapointe DS, Sinha S, Wolfe SA, Brodsky MH. FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system. Nucleic Acids Res : (2011). [Pubmed] |
Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.