Transcription Factor

Accessions: T057701_1.02 (CISBP 1.02), Q9VDZ3 (JASPAR 2024)
Names: sqz, T057701_1.02;, SQZ_DROME
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:B1H, family:C2H2 ZF
Length: 535
Pfam Domains: 158-176 C2H2-type zinc finger
158-180 Zinc finger, C2H2 type
173-197 Zinc-finger double domain
186-208 C2H2-type zinc finger
186-208 Zinc finger, C2H2 type
200-226 Zinc-finger double domain
275-297 C2H2-type zinc finger
275-297 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MAELPTAPNGVPSGDYLHRSIDQLRSLGHLTTAQLVHDYKPFNISEFRQNVAERLDYSLK 60
61 NGLVQHQQQMVMEQQPHPDQQQQQHLHHPQQQQHPPQLKVSYSAPNSPPTPHEQQEQKYD 120
121 PNRSPPRQQMSSASGSGSNGSSPEEESRRGDGDQAKPYKCGSCSKSFANSSYLSQHTRIH 180
181 LGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRCHQT 240
241 DKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKHLQKHAEK 300
301 AEKQQHRHTAQVAAHQQHVPASGIGLNLQRQAMNDVNAAYWAKMGADSAAASLAEAIQQQ 360
361 LPQAGGQPYGNFASLQQQHQQQQQELLHHQRLADTPGHSHSPHEEAAGEDLVLRQSTPQH 420
421 HLQQQQQQQQQQQAQQQQQAQHQPSPGPGNSAFTPLSATVAPPPHLQQHRGPPGSAAAYL 480
481 YQQNAAAAAAAFPTQLISLHQIRNYAHQPGAAGLIAGDHLALGLSAVNAAKEKAQ
Interface Residues: 147, 148, 151, 158, 168, 169, 170, 171, 172, 174, 175, 176, 179, 196, 197, 198, 199, 200, 201, 202, 203, 204, 207, 226, 227, 228, 229, 230, 231, 232, 233, 237, 254, 255, 256, 257, 258, 260, 261, 265, 268, 269, 270, 271, 274, 286, 287, 288, 289, 292, 315, 316, 322, 323, 326, 329
3D-footprint Homologues: 2jpa_A, 2kmk_A, 6jnm_A, 3uk3_C, 8cuc_F, 1tf3_A, 7y3l_A, 5v3j_F, 7n5w_A, 4x9j_A, 5kl3_A, 7ysf_A, 6wmi_A, 5ei9_F, 8ssq_A, 1mey_C, 7w1m_H, 5und_A, 1f2i_J, 5k5i_A, 8ssu_A, 2gli_A, 8gn3_A, 1g2f_F, 5kkq_D, 6u9q_A, 8h9h_G, 7eyi_G, 4m9v_C, 2i13_A, 6e94_A, 2lt7_A, 7y3m_I, 6a57_A, 1ubd_C, 5yel_A, 1llm_D, 7txc_E, 5yj3_D, 2drp_D, 6ml4_A, 6blw_A, 1tf6_A, 2wbs_A
Binding Motifs: M5211_1.02 rvtwhAyaAAAAAAAm
UN0438.1 aaAAAAAAaa
MA2108.1 AAAAAA
Binding Sites: UN0438.1.12
UN0438.1.1
UN0438.1.10
UN0438.1.11
UN0438.1.13
UN0438.1.14
UN0438.1.15
UN0438.1.16
UN0438.1.17
UN0438.1.18
UN0438.1.19
UN0438.1.2
UN0438.1.20
UN0438.1.3
UN0438.1.4 / UN0438.1.5
UN0438.1.6
UN0438.1.7
UN0438.1.8
UN0438.1.9
MA2108.1.1 / MA2108.1.10 / MA2108.1.11 / MA2108.1.12 / MA2108.1.13 / MA2108.1.14 / MA2108.1.15 / MA2108.1.16 / MA2108.1.17 / MA2108.1.18 / MA2108.1.19 / MA2108.1.2 / MA2108.1.20 / MA2108.1.3 / MA2108.1.4 / MA2108.1.5 / MA2108.1.6 / MA2108.1.7 / MA2108.1.8 / MA2108.1.9
Publications: Zhu LJ, Christensen RG, Kazemian M, Hull CJ, Enuameh MS, Basciotta MD, Brasefield JA, Zhu C, Asriyan Y, Lapointe DS, Sinha S, Wolfe SA, Brodsky MH. FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system. Nucleic Acids Res : (2011). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.